Protein Alignment wun2 and Plpp5

DIOPT Version :10

• Sequence 1: NP_524991.1
• Gene: wun2 / 53558
• FlyBaseID: FBgn0041087
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_082276.1
• Gene: Plpp5 / 71910
• MGIID: 1919160
• Length: 260
• Species: Mus musculus
• Alignment Length: 230
• Identity: 72/230 - (31%)
• Similarity: 99/230 - (43%)
• Gaps: 61/230 - (26%)

  Fly   127 RHPYRDST-MPSWILYLMCGALPLTVMLVVEFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLV 190
            |:||.::. .|:..::::....||:::.:.:|.|..|..     .....|....|
Mouse    42 RNPYVEAEYFPTGRMFVIAFLTPLSLIFLAKFLRKADAT-----DSKQACLAASL---------- 91

  Fly   191 ECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAA 255
                       .|.:..:.|||.|..:||.||.|:..|.|   ||...||          .||..
Mouse    92 -----------ALALNGVFTNIIKLIVGRPRPDFFYRCFP---DGLAHSD----------LTCTG 132

  Fly   256 -VDITSKQLKDMRLSFPSGHASFA----CYSMLYLVIYLH------RRMQWKQLRMLCHLLQFLL 309
             .|:    :.:.|.||||||:|||    .::..||...||      |...|:    ||..|..||
Mouse   133 DEDV----VNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKSWR----LCAFLSPLL 189

  Fly   310 LMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVV 344
              ||...||:|..||||||.|||.||.||:|:|.|
Mouse   190 --FAAVIALSRTCDYKHHWQDVLVGSMIGMTFAYV 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	61/165 (37%)
Plpp5	NP_082276.1	PAP2_containing_1_like	39..227	CDD:239484	72/230 (31%)
		Phosphatase sequence motif I. /evidence=ECO:0000250|UniProtKB:Q8NEB5	104..112		3/7 (43%)
		Phosphatase sequence motif II. /evidence=ECO:0000250|UniProtKB:Q8NEB5	145..148		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000250|UniProtKB:Q8NEB5	197..207		6/9 (67%)