DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plpp1

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_038958986.1	Gene:	Plpp1 / 64369	RGDID:	621832	Length:	299	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	102/284 - (35%)
Similarity:	144/284 - (50%)	Gaps:	43/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PPLRGPRQIFG------------RILTD-LCLLSCVGLPMLGFSLWGEAVKRGFFCDDSSLRHPY 130
            ||.|...|:|.            ..||| ..:....|||.:..:......:||.||.|.|:::||
  Rat     2 PPQRCSVQMFSFHYENTADSALCPYLTDNFKINDYPGLPFIILTSRHTPFQRGVFCTDESIKYPY 66

  Fly   131 RDSTMPSWILYLMCGALP----LTVMLVVEFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVE 191
            |:.|:|    |.:.|.:.    :.||:..|........|||    ::..|.:::..:
  Rat    67 REDTIP----YALLGGIVIPFCIIVMITGETLSVYFNVLHS----NSFVSNHYIATI-------- 115

  Fly   192 CYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAV 256
             |..:|.|:||....|..|:|||||||||||||..:|.|.... ..|||     .|||.|.|..
  Rat   116 -YKAVGAFLFGASASQSLTDIAKYSIGRLRPHFLAVCNPDWSK-INCSD-----GYIENFVCQG- 172

  Fly   257 DITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRV 321
              ..:::::.||||.|||:||:.|.||::.:||..||:....|:|..:|||.|:..:.|..|:||
  Rat   173 --NEQKVREGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLVALSIYVGLSRV 235

  Fly   322 SDYKHHWSDVLAGSGIGLTYAVVV 345
            |||||||||||.|...|...|::|
  Rat   236 SDYKHHWSDVLIGLIQGAVVAILV 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	71/155 (46%)
Plpp1	XP_038958986.1	PAP2_wunen	115..260	CDD:239479	71/163 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338332
Domainoid	1	1.000	159	1.000	Domainoid score	I3984
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3693
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D1354951at2759
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm9041
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810