DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and plpp1a

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_697507.5	Gene:	plpp1a / 569053	ZFINID:	ZDB-GENE-080225-26	Length:	282	Species:	Danio rerio

Alignment Length:	258	Identity:	107/258 - (41%)
Similarity:	148/258 - (57%)	Gaps:	27/258 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 ILTDLCLLSCVGLPMLGFSLWG-EAVKRGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLV 154
            ||.|:..|....||:..|:|.. :..:|||||:|.|:|:|:..||:.|.:||.:...||:..|::
Zfish    10 ILLDIACLILADLPLAAFNLGKIKPYQRGFFCNDESIRYPFHSSTVTSTVLYTVGFTLPICSMII 74

  Fly   155 VEFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGR 219
            .|.......|:.|    ::.|:||..|          .|..:|.|:||..:.|..|:||||||||
Zfish    75 GECLSVYLNRIKS----NSFCNGYVAC----------VYKAIGTFVFGAAISQSLTDIAKYSIGR 125

  Fly   220 LRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQ--LKDMRLSFPSGHASFACYSM 282
            |||||..:|:|.... ..|:    |..|||:|.|     |.|:  :.:.||||.|||:||:.|.|
Zfish   126 LRPHFLDVCKPDWSK-INCT----AGAYIEDFVC-----TGKESVVNEGRLSFYSGHSSFSMYCM 180

  Fly   283 LYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVV 345
            |:|.:||..|||.:..|:|...|||.|:..:.||.|:|||||||||||||.|...|...|::|
Zfish   181 LFLALYLQARMQAEWARLLRPTLQFFLIAASVYTGLSRVSDYKHHWSDVLTGLIQGAIVALLV 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	75/157 (48%)
plpp1a	XP_697507.5	PAP2_wunen	98..244	CDD:239479	75/156 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577778
Domainoid	1	1.000	160	1.000	Domainoid score	I4013
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3720
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D1354951at2759
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm6463
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770