DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and plpp2a

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_692261.6	Gene:	plpp2a / 563806	ZFINID:	ZDB-GENE-140703-2	Length:	287	Species:	Danio rerio

Alignment Length:	258	Identity:	86/258 - (33%)
Similarity:	136/258 - (52%)	Gaps:	36/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 ILTDLCLLSCVGLPMLGFSLWGEAVKRGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLVV 155
            :|.||..::.|.:|.:..::......||.:|:|.::::|||    |..|.:.|..|:.::..:::
Zfish    12 VLMDLLCVAVVAMPFIIMTIMYRPYHRGVYCNDETIQYPYR----PDTISHKMMAAVTISCSVII 72

  Fly   156 ----EFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYS 216
                |.:....|||:|              :.:...:....|..:|.|:||..|.|..|::|||:
Zfish    73 IISGEAYLVYTKRLYS--------------NSDFNQYAAALYKVVGTFLFGACVSQSLTDMAKYT 123

  Fly   217 IGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYS 281
            ||||||:|.::|.|.:.:|           |:.|..|..   .::.:.:.||||.|||:||..|.
Zfish   124 IGRLRPNFMSVCAPAVCEG-----------YMLEINCTG---NARNVTESRLSFYSGHSSFGMYC 174

  Fly   282 MLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVV 344
            ||:|.:|:..|:..|..|:|...:||.|:.||.|...|||||||||||||:.|...|...||:
Zfish   175 MLFLALYVQARLASKWARLLRPTIQFFLVAFAIYVGYTRVSDYKHHWSDVVVGLLQGALVAVL 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	65/154 (42%)
plpp2a	XP_692261.6	PAP2_wunen	98..239	CDD:239479	65/154 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577863
Domainoid	1	1.000	160	1.000	Domainoid score	I4013
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3720
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm6463
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.870