DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wun2 and plpp3

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_001919561.1	Gene:	plpp3 / 557680	ZFINID:	ZDB-GENE-060526-241	Length:	312	Species:	Danio rerio

Alignment Length:	310	Identity:	110/310 - (35%)
Similarity:	153/310 - (49%)	Gaps:	63/310 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GPNHNNNNNVKLDLQLPTFVDSTRSQGSLYAVASNKKPPLRGPRQIFGRILTDLCLLSCVGLPML 106
            |.:..|||.|                       :|.|..|.....||       ||:..| ||.|
Zfish    18 GTSTLNNNGV-----------------------NNSKRKLLIALDIF-------CLVLAV-LPFL 51

  Fly   107 GFSLWGEAVK---RGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLVVEFFRGQDKRLH-- 166
              .:....:|   |||:|.|.|:::||::....|..:....|.|.:...:|:    |:..|:|
Zfish    52 --IIETSTIKPYHRGFYCSDQSIQYPYKNGDTISDAVLCAAGILIVIFSIVI----GECYRIHYL 110

  Fly   167 SPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPV 231
            |...||.:.:.|          :...|.::|:||||..|.|..|:|||.|:||:||||..:|:|.
Zfish   111 SQGSKSFVGNPY----------VSALYRQVGVFIFGCAVSQSFTDIAKVSVGRMRPHFLDVCRPN 165

  Fly   232 MKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWK 296
            ... ..||     ..||.|:||..   ...::::.|.||.||||||:.|:||||..||..|..|:
Zfish   166 YST-IDCS-----LGYITEYTCTG---DPSKVQEARKSFFSGHASFSMYTMLYLAFYLQSRFTWR 221

  Fly   297 QLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAG--SGIGLTYAVV 344
            ..|:|..||||.|||.|:||.|:||||:|||.:|||||  .|..:.|.:|
Zfish   222 GARLLRPLLQFTLLMMAFYTGLSRVSDHKHHPTDVLAGFVQGALVAYCIV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	74/156 (47%)
plpp3	XP_001919561.1	PAP2_wunen	125..271	CDD:239479	73/154 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577770
Domainoid	1	1.000	160	1.000	Domainoid score	I4013
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3720
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm6463
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770