DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plpp2

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_056632.2	Gene:	Plpp2 / 50784	MGIID:	1354945	Length:	276	Species:	Mus musculus

Alignment Length:	253	Identity:	93/253 - (36%)
Similarity:	132/253 - (52%)	Gaps:	32/253 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 RQIFGRILTDLCLLSCVGLPMLGFSLWGEAVKRGFFCDDSSLRHPYRDSTMPSWILYLMCGA-LP 148
            |.:|  :|.|:..:....||.:..:|.....||||:|.|.|:|:|||..|:...   ||.|. :.
Mouse     4 RWVF--VLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHG---LMAGVIIT 63

  Fly   149 LTVMLVV--EFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTN 211
            .||:||.  |.:.....||:|.       |.::       .::...|..:|.|:||..|.|..|:
Mouse    64 ATVILVSLGEAYLVYTDRLYSR-------SNFN-------NYVAAIYKVLGTFLFGAAVSQSLTD 114

  Fly   212 IAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHAS 276
            :|||.||||||.|..:|.|....       :|.:.|::...|..   :...:.:.||||.|||:|
Mouse   115 LAKYMIGRLRPSFLAVCDPDWSQ-------VNCSGYVQLEVCRG---SPANVTEARLSFYSGHSS 169

  Fly   277 FACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAG 334
            |..|.||:|.:|:..|:.||..|:|...:||.|:.||.|...|||||:||||||||.|
Mouse   170 FGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVG 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	62/144 (43%)
Plpp2	NP_056632.2	PAP2_wunen	94..239	CDD:239479	62/144 (43%)
		Phosphatase sequence motif I. /evidence=ECO:0000250\|UniProtKB:O34349	117..125		6/7 (86%)
		Phosphatase sequence motif II. /evidence=ECO:0000250\|UniProtKB:O34349	164..167		1/2 (50%)
		Phosphatase sequence motif III. /evidence=ECO:0000250\|UniProtKB:O34349	212..223		9/10 (90%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..276
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834794
Domainoid	1	1.000	159	1.000	Domainoid score	I4068
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3731
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm8794
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870