DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and slc38a9

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001011337.1	Gene:	slc38a9 / 496801	XenbaseID:	XB-GENE-5823434	Length:	554	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	56/293 - (19%)
Similarity:	90/293 - (30%)	Gaps:	104/293 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LYAVASNKKPPLRGPRQIFGRILTDLCLLSCVGLPM--LGFSL---WGEAVKRGFFCDDSSLRHP 129
            |..:.|.:.|.......|.|.: :.:.|:|.|.|..  |||.|   |.:.  :.||..:..|..|
Frog   292 LLPLLSFRSPSFFAKFNILGTV-SIIYLVSLVTLKAAHLGFHLRFSWNQV--QEFFVPEFRLSFP 353

  Fly   130 -------------------------YRDSTMPSWILYLMCG---------------ALPLTVMLV 154
                                     .:::.....|.||:.|               :.||:...:
Frog   354 QLTGILTLAFFIHNCIITLLKNNRNQKNNVRDLSIAYLLVGLTYIYVGVAVFASFPSPPLSKQCI 418

  Fly   155 VEFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMG----------IF--IFGLGVEQ 207
            .:.|...       ||.|.:.:  .:..:.|...::..|..:|          ||  |:......
Frog   419 QQNFLDN-------FPSSDILA--FVARIFLLFQMMTVYPLLGYLVRVQLLGHIFGDIYPSVFHV 474

  Fly   208 LSTNIAKYSIGRLRPHFYTLCQPVMK-DGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFP 271
            |:.|||...:|.:...||.....::: .|..|
Frog   475 LALNIAVVGVGVIMARFYPNIGGIIRFSGAAC--------------------------------- 506

  Fly   272 SGHASFACYSMLYLVIYLHRRMQWKQLRMLCHL 304
             |.|....|..|..:|.||||.|.|...:|.|:
Frog   507 -GLAFVFVYPSLIHMISLHRRGQLKVHSILIHV 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	27/127 (21%)
slc38a9	NP_001011337.1	SLC5-6-like_sbd	108..520	CDD:382020	47/273 (17%)
slc38a9	NP_001011337.1	Important for arginine binding and amino acid transport. /evidence=ECO:0000250\|UniProtKB:Q08BA4	122..127
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4216
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000