DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Sgpp2

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001004173.1	Gene:	Sgpp2 / 433323	MGIID:	3589109	Length:	354	Species:	Mus musculus

Alignment Length:	151	Identity:	33/151 - (21%)
Similarity:	56/151 - (37%)	Gaps:	42/151 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 IFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQ 262
            |::..:.:.|::.:|.|:.    ||.|    .||::         ...|.|.|:
Mouse    79 IWVLVMYIGQVAKDILKWP----RPSF----PPVVR---------LEKRIIAEY----------- 115

  Fly   263 LKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHH 327
                  ..||.||..|......|:|....|.|:..:..|     .:.::|:....|:|:....|.
Mouse   116 ------GMPSTHAMAATAISFTLLISTMDRYQYPFILGL-----MMAVVFSTLVCLSRLYTGMHT 169

  Fly   328 WSDVLAGSGIGLTYAVVVTST 348
            ..|:|.|.   |..||::..|
Mouse   170 VLDILGGV---LITAVLIALT 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	32/147 (22%)
Sgpp2	NP_001004173.1	PAP2_SPPase1	39..188	CDD:239482	33/151 (22%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	91..99		2/11 (18%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	118..121		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	161..172		2/10 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900