DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and laza

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_649391.1	Gene:	laza / 40468	FlyBaseID:	FBgn0037163	Length:	334	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	96/235 - (40%)
Similarity:	143/235 - (60%)	Gaps:	24/235 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 KRGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLVVEFFRGQDKRLHSPFPKSTMCSGYHL 180
            ||||||.|.|:|:||:|.|:...:|.||...||:..:.|||..|              :|..:..
  Fly     5 KRGFFCSDLSIRYPYKDCTITVPMLLLMMLLLPMLFVAVVEIMR--------------ICKRFRT 55

  Fly   181 CHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAA 245
            .......|..|     ..|.||.....|:|.:||:::|||||||:..|||.:.||::|||..||.
  Fly    56 RLYFRNLWRAE-----ATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQNAE 115

  Fly   246 RYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWK---QLRMLCHLLQF 307
            .|:|:|.|...:::::|::::.:||||.|:|.:.|||:.|.:|:|.  .|:   .:|:|.|:|||
  Fly   116 LYVEQFHCTNNNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHG--VWRGRGGVRVLRHVLQF 178

  Fly   308 LLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVVTS 347
            ||||.|...:|:||:||.|||||||||:.:|:|||.:..:
  Fly   179 LLLMAALCVSLSRVADYWHHWSDVLAGALLGVTYAAITAA 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	72/157 (46%)
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	73/161 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468188
Domainoid	1	1.000	122	1.000	Domainoid score	I3483
eggNOG	1	0.900	-	-		E1_COG0671
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	78	1.000	Inparanoid score	I1868
Isobase	1	0.950	-	0	Normalized mean entropy	S2488
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		otm14189
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.880