DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and plpp2b

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_956247.1	Gene:	plpp2b / 335485	ZFINID:	ZDB-GENE-030131-7425	Length:	273	Species:	Danio rerio

Alignment Length:	264	Identity:	85/264 - (32%)
Similarity:	133/264 - (50%)	Gaps:	34/264 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 GPRQIFGRILTDLCLLSCVGLPMLGFSLWGEAVKRGFFCDDSSLRHPYRDSTMPSWILYLMCGAL 147
            |.:::|  :|.|:..:....||.:..::.....:||.||.|.|:.:|.:..|:.:  :.|....:
Zfish     2 GKKKLF--VLVDVMCVVVASLPFVAMTIASHPYERGIFCQDESIGYPVKTDTITN--VTLAAVTI 62

  Fly   148 PLTVMLVV--EFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLST 210
            ..|::::.  |.:....|::||              :.....::...|..:|.|:||..|.|..|
Zfish    63 TCTILIICSGEAYLVYSKKIHS--------------NSSFNQYVSAIYKVLGAFLFGGAVSQSLT 113

  Fly   211 NIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHA 275
            ::|||:|||.||:|..:|.|     ..|...:|    :...|....|:|     :.||||.|||:
Zfish   114 DLAKYTIGRPRPNFLAVCAP-----KVCKGFVN----LNNCTGNPADVT-----EARLSFYSGHS 164

  Fly   276 SFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLT 340
            |||.|.||:|..|:..|:..|..|:|...:||.|:.||.|...|||||||||||||:.|...|..
Zfish   165 SFAMYCMLFLAFYVQARLNAKWARLLRPTIQFFLVAFAVYVGYTRVSDYKHHWSDVMVGLLQGAL 229

  Fly   341 YAVV 344
            .|::
Zfish   230 IAIL 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	65/154 (42%)
plpp2b	NP_956247.1	PAP2_wunen	94..235	CDD:239479	65/154 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577864
Domainoid	1	1.000	160	1.000	Domainoid score	I4013
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3720
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm6463
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770