DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plppr3

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_853665.2	Gene:	Plppr3 / 314614	RGDID:	727823	Length:	716	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	74/286 - (25%)
Similarity:	126/286 - (44%)	Gaps:	45/286 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KKPPLRGPRQIFGRILTDLCLLSC---VGLPMLGFSLWG----------EAVKRGFFCDDSSLRH 128
            ||...:.|:.       .:.||.|   |.||::..|:..          :..|.||.|.|.||..
  Rat     4 KKEKNKTPKD-------SMTLLPCFYFVELPIVASSVVSLYFLELTDLFQPAKVGFQCHDRSLSM 61

  Fly   129 PY---RDSTMPSWILYLMCGALPLTVMLVVEFFRGQ----DKRLHSPFP---KSTMCSGYHLCHL 183
            ||   .:..:|..:|..:..|.|...::|.|   |.    ..||....|   :.::.:|.  |:.
  Rat    62 PYVETNEELIPLLMLLSLAFAAPAASIMVGE---GMVYCLQSRLWGRGPGGVEGSINAGG--CNF 121

  Fly   184 ELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQP-VMKDGTTCSDPINAARY 247
            .  ::|......:|:.:|||....|.|::.:.:.|...|.|.|:|:| ....||:|    .|..|
  Rat   122 N--SFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSC----EANPY 180

  Fly   248 IEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMF 312
            |.:..|:..|  :..:...|.:|||.||:.:.::.:|:.:|.:..:. ...::|..:|.|...:.
  Rat   181 ITQDICSGHD--THAILSARKTFPSQHATLSAFAAVYVSMYFNSVIS-DATKLLKPILVFAFAIA 242

  Fly   313 AWYTALTRVSDYKHHWSDVLAGSGIG 338
            |....||:::.|:.|..||.||..||
  Rat   243 AGVCGLTQITQYRSHPVDVYAGFLIG 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	42/149 (28%)
Plppr3	NP_853665.2	PAP2_wunen	127..276	CDD:239479	42/149 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..334
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..488
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	548..589
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	664..694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338369
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740