DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plppr4

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001001508.2	Gene:	Plppr4 / 295401	RGDID:	727806	Length:	766	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	85/296 - (28%)
Similarity:	136/296 - (45%)	Gaps:	45/296 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 GPRQIF---------GRILTD-LCLLSC---VGLPMLGFSLWG----------EAVKRGFFCDDS 124
            |.||:.         |:::.| :.||.|   |.||:|..|:..          :.|..||.|.|.
  Rat    43 GARQVAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDR 107

  Fly   125 SLRHPYRDST---MPSWILYLMCGALPLTVMLVVE--FFRGQDKRLHSPFPKSTMCSGYHLCHLE 184
            ||..||.:.|   :|..:|..:..|.|...::|.|  .:....||.:....:..:.:|.  |:..
  Rat   108 SLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGG--CNFN 170

  Fly   185 LPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIE 249
              ::|......:|:.:|||....|.|:|.:.|.|...|:|.|:|:|   :.|:.:.......||.
  Rat   171 --SFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKP---NYTSLNVSCKENSYIV 230

  Fly   250 EFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAW 314
            |..|:..|:|  .:...|.||||.||:.|.::.:|:.:|.:..:. ...::|..||.|..::...
  Rat   231 EDICSGSDLT--VINSGRKSFPSQHATLAAFAAVYVSMYFNSTLT-DSSKLLKPLLVFTFIICGI 292

  Fly   315 YTALTRVSDYKHHWSDV----LAGSGIGL---TYAV 343
            ...|||::.||:|..||    |.|.||.|   .|||
  Rat   293 ICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAV 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	51/160 (32%)
Plppr4	NP_001001508.2	PAP2_wunen	175..324	CDD:239479	48/154 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	454..503
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	510..529
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	634..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	672..705
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	741..766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338340
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740