DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plppr4

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_808332.3	Gene:	Plppr4 / 229791	MGIID:	106530	Length:	766	Species:	Mus musculus

Alignment Length:	281	Identity:	82/281 - (29%)
Similarity:	132/281 - (46%)	Gaps:	36/281 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GRILTD-LCLLSC---VGLPMLGFSLWG----------EAVKRGFFCDDSSLRHPYRDST---MP 136
            |:::.| :.||.|   |.||:|..|:..          :.|..||.|.|.||..||.:.|   :|
Mouse    58 GKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIP 122

  Fly   137 SWILYLMCGALPLTVMLVVE--FFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIF 199
            ..:|..:..|.|...::|.|  .:....||.:....:..:.:|.  |:..  ::|......:|:.
Mouse   123 FLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGG--CNFN--SFLRRAVRFVGVH 183

  Fly   200 IFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLK 264
            :|||....|.|:|.:.|.|...|:|.|:|:|   :.|:.:.......||.|..|:..|:|  .:.
Mouse   184 VFGLCSTALITDIIQLSTGYQAPYFLTVCKP---NYTSLNVSCKENSYIVEDICSGSDLT--VIN 243

  Fly   265 DMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWS 329
            ..|.||||.||:.|.::.:|:.:|.:..:. ...::|..||.|..::......|||::.||:|..
Mouse   244 SGRKSFPSQHATLAAFAAVYVSMYFNSTLT-DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPV 307

  Fly   330 DV----LAGSGIGL---TYAV 343
            ||    |.|.||.|   .|||
Mouse   308 DVYCGFLIGGGIALYLGLYAV 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	51/160 (32%)
Plppr4	NP_808332.3	PAP2_wunen	175..324	CDD:239479	48/154 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	454..494
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	634..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	672..701
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	742..766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834758
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740