DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and Plpp1

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_032273.1	Gene:	Plpp1 / 19012	MGIID:	108412	Length:	284	Species:	Mus musculus

Alignment Length:	253	Identity:	100/253 - (39%)
Similarity:	142/253 - (56%)	Gaps:	26/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 LCLLSCVGLPMLGFSLWGEA--VKRGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLVVEF 157
            :|:| ...:||....| |:.  .:|||||.|:|:::||.|||:||.||.::...||:..|.:.|.
Mouse    15 ICVL-LAAMPMTILKL-GKVYPFQRGFFCTDNSVKYPYHDSTIPSRILAILGLGLPIFSMSIGES 77

  Fly   158 FRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRP 222
            .......|||   .|.:.:.|          :...|..:|.|:||:...|..|:||||:||.|||
Mouse    78 LSVYFNVLHS---NSFVGNPY----------IATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRP 129

  Fly   223 HFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVI 287
            ||..:|.|.... ..|||     .|||::.|..   ..:::|:.||||.|||:||:.|.||::.:
Mouse   130 HFLAICNPDWSK-INCSD-----GYIEDYICQG---NEEKVKEGRLSFYSGHSSFSMYCMLFVAL 185

  Fly   288 YLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVV 345
            ||..||:....|:|..:|||.|:.|:.|..|:||||||||||||..|...|...|::|
Mouse   186 YLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAAMAILV 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	69/155 (45%)
Plpp1	NP_032273.1	PAP2_wunen	99..244	CDD:239479	69/154 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834750
Domainoid	1	1.000	159	1.000	Domainoid score	I4068
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3731
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm8794
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800