DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and SGPP2

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_689599.2	Gene:	SGPP2 / 130367	HGNCID:	19953	Length:	399	Species:	Homo sapiens

Alignment Length:	176	Identity:	36/176 - (20%)
Similarity:	64/176 - (36%)	Gaps:	43/176 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 YHLCHLELPTWLVECY---HRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCS 239
            :::..|....|.::.|   ..:.|::..:.:.|::.::.|:.    ||.    ..||:|
Human   101 FYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWP----RPS----SPPVVK------ 151

  Fly   240 DPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHL 304
               ...|.|.|:                 ..||.||..|......|:|....|.|:..:..|
Human   152 ---LEKRLIAEY-----------------GMPSTHAMAATAIAFTLLISTMDRYQYPFVLGL--- 193

  Fly   305 LQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVVTSTMW 350
              .:.::|:....|:|:....|...|||.|..| ....:|:|...|
Human   194 --VMAVVFSTLVCLSRLYTGMHTVLDVLGGVLI-TALLIVLTYPAW 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	32/157 (20%)
SGPP2	NP_689599.2	PAP2_SPPase1	84..233	CDD:239482	34/171 (20%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	136..144		1/11 (9%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	163..166		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	206..217		2/10 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900