| Sequence 1: | NP_001260760.1 | Gene: | esn / 53557 | FlyBaseID: | FBgn0263934 | Length: | 1134 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055055.1 | Gene: | LIMD1 / 8994 | HGNCID: | 6612 | Length: | 676 | Species: | Homo sapiens |
| Alignment Length: | 506 | Identity: | 115/506 - (22%) |
|---|---|---|---|
| Similarity: | 169/506 - (33%) | Gaps: | 114/506 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 342 PAPRSSGNMQQAPQQQQHPHPPSSSYYTQTESELLQIEAGG-------------TGLTFASHSQR 393
Fly 394 -----PESAISQVA--------STAHLDVPSAASSGSGGSAVSGGSGGAPESAGRF----VSPLQ 441
Fly 442 RRHCQPPSHLPLNSVASPLRTASYKSAAAVAGHGFHHSHHQQLDFQRNSQSDDDSGCALEEYTWV 506
Fly 507 PPGLRPDQVRLYFSQLPD---DKVPY-VNSPGEKYRVKQLLHQLPPQDNEVRY-CHSLSDEERKE 566
Fly 567 LRIFSAQRKREALGRGAVRLLSDERP-------CKGCEEPLSGGDIVVFAQRLGAQLC------W 618
Fly 619 HPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHA----ETQKPRCSACDEIIFSDECTEAEGRTWH 679
Fly 680 MKHFACQECEHQLGGQRY-IMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQ------MSHDGQ 737
Fly 738 HWHATDQCFSCCTCRCSLL---GRPFLPRRGTIYCSIACSKGEPPTPSDTS 785 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| esn | NP_001260760.1 | PET_Prickle | 492..588 | CDD:193602 | 28/100 (28%) |
| LIM1_Prickle | 593..651 | CDD:188799 | 13/63 (21%) | ||
| LIM2_Prickle | 656..711 | CDD:188802 | 17/55 (31%) | ||
| LIM3_Prickle | 716..774 | CDD:188804 | 15/66 (23%) | ||
| LIMD1 | NP_055055.1 | Mediates nuclear export | 54..134 | ||
| Atrophin-1 | <69..443 | CDD:331285 | 57/262 (22%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 104..163 | ||||
| Interaction with EGLN1/PHD2 | 186..260 | 8/53 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 189..389 | 38/193 (20%) | |||
| Interaction with RB1. /evidence=ECO:0000269|PubMed:15542589 | 404..442 | 13/43 (30%) | |||
| Necessary for nuclear localization | 472..676 | 50/213 (23%) | |||
| LIM1_Ajuba_like | 472..525 | CDD:188738 | 13/62 (21%) | ||
| LIM2_Ajuba_like | 537..589 | CDD:188741 | 16/52 (31%) | ||
| LIM3_Ajuba_like | 597..658 | CDD:188822 | 15/63 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1704 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||