Protein Alignment esn and ZNF185

DIOPT Version :9

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: XP_016885310.1
• Gene: ZNF185 / 7739
• HGNCID: 12976
• Length: 766
• Species: Homo sapiens
• Alignment Length: 798
• Identity: 159/798 - (19%)
• Similarity: 236/798 - (29%)
• Gaps: 308/798 - (38%)

  Fly    38 ANTATTISDSSTTTASSGSPTRHRSCDSLSKSSQAEAGKLFPRNMPSIRRSRRRAVSAERERLAS 102
            ||.....:.|...||::|.|   |...|..|.:..:..||.|.|:      ||.:.|.:.|
Human   108 ANGTPKSAASLVRTANAGPP---RPSSSGYKMTTEDYKKLAPYNI------RRSSTSGDTE---- 159

  Fly   103 RERLEEQVQPPKMPQIGAGQQSRLS-----TVTKLTPRKQSSKSTCSKHRGNAPAKCIIKSAVRT 162
             |..||:|.|     ..:.:|.|.|     .:.:..||:.|...:.:|....:|
Human   160 -EEEEEEVVP-----FSSDEQKRRSEAASGVLRRTAPREHSYVLSAAKKSTGSP----------- 207

  Fly   163 KTKPKATTITLAPY-----EIALE-LPNE--SPAPTLAMAVAQSSGC------------VQRKLS 207
                  |..|.||:     |:..| .|:|  ...|.||.:...|:..            ::...|
Human   208 ------TQETQAPFIAKRVEVVEEDGPSEKSQDPPALARSTPGSNSADGGRTKASRAIWIECLPS 266

  Fly   208 SEDQFHSSGISCNGETDDDVEVAMLTGSLTPSQIARIQGQQILRYDDLRNLNRCRNRNAVWLNP- 271
            ......|..:|..||     |:..|. .|||....|:....:   :.:|:....:::.|    |
Human   267 MPSPAGSQELSSRGE-----EIVRLQ-ILTPRAGLRLVAPDV---EGMRSSPGNKDKEA----PC 318

  Fly   272 -KDTEQLLEVDKSRRKANCYFNQAIADDIQLSD-------------------------------- 303
             ::.::.|..:::.|..|   ..|.....||||
Human   319 SRELQRDLAGEEAFRAPN---TDAARSSAQLSDGNVGSGATGSRPEGLAAVDIGSERGRLCAAAS 380

  Fly   304 ----IEEQLARFDGHSKR----PPPPAATAPKITQPSQVIEKFKPTPAPRSSGNMQQAPQQQQHP 360
                :|:|    ||||..    .|.|||.:...|..|.|       ||.|.|.:.......:..|
Human   381 FASFLEDQ----DGHSANSQSCKPRPAAISSSATSVSAV-------PADRKSNSTAAQEDAKADP 434

  Fly   361 HPPSSSYYTQTESELLQIEAGGTGLTFASHSQRPESAISQVASTAHLDVPSAASSGSGGSAVSGG 425
            ....:.|    |.:.:....|                      .|..:.|.|...|.|..||...
Human   435 KGALADY----EGKDVATRVG----------------------EAWQERPGAPRGGQGDPAVPAQ 473

  Fly   426 SGGAPESAGRFVSP------LQRRHC------QP---PSHLP----------------------- 452
            ....|.:..|..||      ::|..|      ||   |..:|
Human   474 QPADPSTPERQSSPSGSEQLVRRESCGSRRVPQPDSSPKKIPPLPCGGPGQGSIRRDKAGGHIGD 538

  Fly   453 --LNSVASPLRTASYKSAAAVAGHGFHH--------------SHHQQLD----FQRNSQSDDDSG 497
              |...||.|.....|..|...|..:..              ...|..|    .|:||.|..:..
Human   539 CLLTPGASVLTDFEGKDVATKVGEAWQDRPGAPRGGQGDPAVPTQQPADPSTPEQQNSPSGSEQF 603

  Fly   498 CALEEYT-----------WVPPGLRPDQVRLYF----SQLPDDKV--------PYVN----SPGE 535
            ...|..|           .|......:|..:|.    |:|.....        .|||    |.|:
Human   604 VRRESCTSRVRSPSSCMVTVTVTATSEQPHIYIPAPASELDSSSTTKGILFVKEYVNASEVSSGK 668

  Fly   536 KYRVKQLLHQLPPQDNEVRYCHSLSDEERKELRIFSAQRKREALGRGAVRLLSDERPCKGC--EE 598
            ..              ..||.:..|.|:.     |:.::|               .||...  .|
Human   669 PV--------------SARYSNVSSIEDS-----FAMEKK---------------PPCGSTPYSE 699

  Fly   599 PLSGGDIVVFAQR------------LGAQLCWHPGCFVCSVCKEL---LVDLIYFQRDGNLYCGR 648
            ..:|| |..:..|            ||  :|.|..||.|.:|.:.   |:|.|:..|| .::||:
Human   700 RTTGG-ICTYCNREIRDCPKITLEHLG--ICCHEYCFKCGICSKPMGDLLDQIFIHRD-TIHCGK 760

  Fly   649 HHAETQKPRCSACDEIIF 666
                        |.|.:|
Human   761 ------------CYEKLF 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	19/122 (16%)
		LIM1_Prickle	593..651	CDD:188799	21/74 (28%)
		LIM2_Prickle	656..711	CDD:188802	3/11 (27%)
		LIM3_Prickle	716..774	CDD:188804
ZNF185	XP_016885310.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900