DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esn and Lmcd1

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_001008562.1	Gene:	Lmcd1 / 494021	RGDID:	1308963	Length:	365	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	91/242 - (37%)
Similarity:	118/242 - (48%)	Gaps:	35/242 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   503 YTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEERKEL 567
            |.|.|||:.......|...:|.:|.|...:.|..||.:||:||||..|.:...|..|.:.|.|.:
  Rat   118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLVENELKAM 182

  Fly   568 RIFSAQRKREALGRGAVRL-----------LSDERP------------------------CKGCE 597
            ..|..|.|.||||.|.|.|           .:.|:|                        |:.|:
  Rat   183 EEFVKQYKSEALGVGEVALPGQGGLPKEENKTQEKPEGTETTAPTTNGSLGDPSKEVEYVCELCK 247

  Fly   598 EPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACD 662
            ........||:|.|.|....|||.||:|..|.|.|||||||.:||..:||||:.|:.:||||.||
  Rat   248 GVAPADSPVVYADRAGYSKQWHPTCFLCIKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCD 312

  Fly   663 EIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLAC 709
            |||||::....|...||.|||.|:.||..|.|:.||:.:|:..|..|
  Rat   313 EIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAYIITKGQLLCPTC 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	33/95 (35%)
		LIM1_Prickle	593..651	CDD:188799	28/57 (49%)
		LIM2_Prickle	656..711	CDD:188802	27/54 (50%)
		LIM3_Prickle	716..774	CDD:188804
Lmcd1	NP_001008562.1	PET_testin	116..203	CDD:193604	33/84 (39%)
		LIM1_Testin_like	243..300	CDD:188726	27/56 (48%)
		LIM	306..359	CDD:413332	26/52 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820