DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esn and fhl3

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_001008165.1	Gene:	fhl3 / 493527	XenbaseID:	XB-GENE-947662	Length:	279	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	67/235 - (28%)
Similarity:	108/235 - (45%)	Gaps:	48/235 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   557 HSLSDEERKELRIFSAQRKREALGRGAVRLLSDE-------RPCKGCEEPLSGGDIVVFAQRL-- 612
            |||:||.      |:.|.:         .||.::       ..|..||:.:..|     :::|
Frog    73 HSLADEP------FTCQDE---------ELLCNDCYCNEFSSKCISCEKTVMPG-----SRKLEY 117

  Fly   613 GAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDE------IIFSDECT 671
            ..| .||..||:|:.|::.:....:...:.|.||...:.....|||:.|.:      :.:.||
Frog   118 NGQ-TWHEHCFICNSCQQPIGSRSFIPENQNHYCIPCYESKLAPRCTHCKKSLTKGGVTYRDE-- 179

  Fly   672 EAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQG--QMSH 734
                 .||.:.|.|..|:.||.||::..::.||||:.||..::|:.|..|.:.|....|  .:|.
Frog   180 -----PWHKECFVCTGCKTQLAGQQFTSQDEKPYCIKCFGNLYAKKCAGCTKPITGFGGAKYVSF 239

  Fly   735 DGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACS 774
            :.:|||  ..||:|..|..||:|:.|:|....|.|. ||:
Frog   240 EERHWH--HSCFNCSRCSTSLVGKGFIPDNEDILCR-ACN 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	8/30 (27%)
		LIM1_Prickle	593..651	CDD:188799	15/59 (25%)
		LIM2_Prickle	656..711	CDD:188802	20/60 (33%)
		LIM3_Prickle	716..774	CDD:188804	20/59 (34%)
fhl3	NP_001008165.1	LIM	<5..33	CDD:351770
		LIM1_FHL3	36..94	CDD:188807	9/35 (26%)
		LIM2_FHL3	98..155	CDD:188811	15/62 (24%)
		LIM3_FHL	162..213	CDD:188732	17/57 (30%)
		LIM4_FHL3	221..276	CDD:188818	20/57 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910