Protein Alignment esn and LIMS1

DIOPT Version :9

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: NP_001358423.1
• Gene: LIMS1 / 3987
• HGNCID: 6616
• Length: 398
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 79/365 - (21%)
• Similarity: 116/365 - (31%)
• Gaps: 134/365 - (36%)

  Fly   523 PDDKVPYVNSPGEKYRVK-----QLLHQLPP----QDNEVRYCHSLSDEERKELRIFSAQRKREA 578
            |.:|:  |||.||.|..:     |...|.|.    :....:||      |.....:|:
Human    81 PAEKI--VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC------EHDFQMLFA------- 130

  Fly   579 LGRGAVRLLSDERPCKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDL-------- 635
                         ||  |.:   .|:.::..........|||.||.|.:|:|:|.|:
Human   131 -------------PC--CHQ---CGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGR 177

  Fly   636 -------------------------------IYFQRD------------------------GNLY 645
                                           :.|:.|                        |.||
Human   178 HLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 242

  Fly   646 CGRHHAETQKPRCSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACF 710
            |...|.:...|.|.||...| ......|.|:.||::||.|.:||....|.|:..|:|..||...:
Human   243 CLPCHDKMGVPICGACRRPI-EGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHY 306

  Fly   711 DTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSK 775
            :.:|.:.|.:|..||..|  .:|...:.|..  .||:|.||...|
Human   307 NQLFGDVCFHCNRVIEGD--VVSALNKAWCV--NCFACSTCNTKL-------------------- 347

  Fly   776 GEPPTPSDTSSGPQLRPTHRASTSSQIAKSPRRGGERERD 815
                |..|......|:|..:........:..||..:|||:
Human   348 ----TLKDKFVEIDLKPVCKHCYEKMPEEFKRRLAKRERE 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	15/73 (21%)
		LIM1_Prickle	593..651	CDD:188799	19/120 (16%)
		LIM2_Prickle	656..711	CDD:188802	20/54 (37%)
		LIM3_Prickle	716..774	CDD:188804	13/57 (23%)
LIMS1	NP_001358423.1	LIM1_PINCH	72..130	CDD:188717	14/56 (25%)
		LIM2_PINCH	133..184	CDD:188718	12/53 (23%)
		LIM3_PINCH	197..247	CDD:188719	6/49 (12%)
		LIM4_PINCH	253..306	CDD:188720	20/53 (38%)
		LIM5_PINCH	314..367	CDD:188721	17/80 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910