DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esn and Fhl4

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_001013190.2	Gene:	Fhl4 / 314678	RGDID:	1308978	Length:	280	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	57/197 - (28%)
Similarity:	91/197 - (46%)	Gaps:	33/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   593 CKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPR 657
            ||||.:.:..|:..|  :..|.  .||..|||||.|||::....:|.:|...|
  Rat   100 CKGCLKDIKQGEQSV--EYKGT--IWHKDCFVCSNCKEVIGTKTFFPKDEGFY------------ 148

  Fly   658 CSACDEIIFSDECTEA-----------EGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFD 711
            |.||.:|:|:..|.:.           :.:.||.:.|.|..|..:|..||:.:.:.|.:|:.|:.
  Rat   149 CVACYDILFTKYCVKCNKPITSGGVSYQDQPWHSECFVCVNCSKELSEQRFTVMDDKIFCVDCYK 213

  Fly   712 TMFAEYCDYC-GEVIGVDQGQ--MSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIAC 773
            ...|:.|..| ..:.|..:|.  ::|:...||  |.||:|..|..:|..:.|:..:..|||. .|
  Rat   214 NFIAKKCAGCKNPITGFGKGSNVVTHETNSWH--DYCFNCKACSVNLANKHFVFHQEQIYCP-DC 275

  Fly   774 SK 775
            :|
  Rat   276 AK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602
		LIM1_Prickle	593..651	CDD:188799	20/57 (35%)
		LIM2_Prickle	656..711	CDD:188802	17/65 (26%)
		LIM3_Prickle	716..774	CDD:188804	17/60 (28%)
Fhl4	NP_001013190.2	LIM	39..91	CDD:413332
		LIM	100..157	CDD:413332	24/72 (33%)
		LIM	161..213	CDD:413332	12/51 (24%)
		LIM	216..279	CDD:413332	20/65 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910