DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment esn and Fhl3

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_001101449.1	Gene:	Fhl3 / 313582	RGDID:	1307180	Length:	288	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	73/247 - (29%)
Similarity:	107/247 - (43%)	Gaps:	47/247 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   554 RYC---HSLSDEERKELRIFSAQRKREALGRGAVRLLSDE-------RPCKGCEEPLSGGDIVVF 608
            |.|   .||:||.      |:.|..         .||.:|       ..|..|.|.:..|
  Rat    67 RCCRCQRSLADEP------FTCQDS---------ELLCNECYCTAFSSQCSACGETVMPG----- 111

  Fly   609 AQRL--GAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDEIIFSDECT 671
            :::|  |.| .||..||:||.|::.|....:....|..||...:.....|||:.|.:.:.....|
  Rat   112 SRKLEYGGQ-TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVT 175

  Fly   672 EAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYC---------GEVIGV 727
            ..: :.||.:...|..|:..|.||::..|:..|||:|||..:||..|..|         .|..|:
  Rat   176 YRD-QPWHRECLVCTGCQTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSGSEGAGL 239

  Fly   728 DQGQ-MSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSKGEP 778
            ..|: :|.:.:|||  ..||||..|..||:|:.|:|....:.|. .||:..|
  Rat   240 GGGKYVSFEDRHWH--HSCFSCARCSTSLVGQGFVPDGDQVLCQ-GCSQAGP 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	9/36 (25%)
		LIM1_Prickle	593..651	CDD:188799	18/59 (31%)
		LIM2_Prickle	656..711	CDD:188802	18/54 (33%)
		LIM3_Prickle	716..774	CDD:188804	20/67 (30%)
Fhl3	NP_001101449.1	LIM	<5..33	CDD:413332
		LIM1_FHL3	36..94	CDD:188807	11/41 (27%)
		LIM2_FHL3	98..155	CDD:188811	18/62 (29%)
		LIM3_FHL	162..213	CDD:188732	15/51 (29%)
		LIM	221..284	CDD:413332	20/65 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810