Protein Alignment esn and LMCD1

DIOPT Version :10

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: NP_055398.1
• Gene: LMCD1 / 29995
• HGNCID: 6633
• Length: 365
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 93/245 - (37%)
• Similarity: 119/245 - (48%)
• Gaps: 41/245 - (16%)

  Fly   503 YTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEERKEL 567
            |.|.|||:.......|...:|.:|.|...:.|..||.:||:||||..|.:...|..|.:.|.|.:
Human   118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLM 182

  Fly   568 RIFSAQRKREALGRGAVRL-----------LSDERP---------------------------CK 594
            ..|..|.|.||||.|.|.|           ...|:|                           ||
Human   183 EEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCK 247

  Fly   595 GCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCS 659
            |...|.|.   ||::.|.|....|||.||||:.|.|.|||||||.:||..:||||:.|:.:||||
Human   248 GAAPPDSP---VVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCS 309

  Fly   660 ACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLAC 709
            .||||||:::....|...||.|||.|:.||..|.|:.||:.:|:..|..|
Human   310 GCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	33/95 (35%)
		LIM1_Prickle	593..651	CDD:188799	31/57 (54%)
		LIM2_Prickle	656..711	CDD:188802	26/54 (48%)
		LIM3_Prickle	716..774	CDD:188804
LMCD1	NP_055398.1	PET_testin	116..203	CDD:193604	33/84 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		3/34 (9%)
		LIM1_Testin_like	243..300	CDD:188726	30/59 (51%)
		LIM	306..359	CDD:413332	25/52 (48%)