Protein Alignment esn and FHL3

DIOPT Version :10

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: NP_004459.2
• Gene: FHL3 / 2275
• HGNCID: 3704
• Length: 280
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 69/238 - (28%)
• Similarity: 106/238 - (44%)
• Gaps: 48/238 - (20%)

  Fly   549 QDNEVR----YCHSLSDEERKELRIFSAQRKREALGRGAVRLLSDERPCKGCEEPLSGGDIVVFA 609
            ||:|:.    ||.:           ||:|                   |..|.|.:..|     :
Human    83 QDSELLCNDCYCSA-----------FSSQ-------------------CSACGETVMPG-----S 112

  Fly   610 QRL--GAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDEIIFSDECTE 672
            ::|  |.| .||..||:||.|::.|....:....|..||...:.....|||:.|.:.:.....|.
Human   113 RKLEYGGQ-TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTY 176

  Fly   673 AEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGE-VIGVDQGQ-MSHD 735
            .: :.||.:...|..|:..|.||::..|:..|||:|||..:||..|..|.. ::|:..|: :|.:
Human   177 RD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240

  Fly   736 GQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSKGEP 778
            .:|||  ..||||..|..||:|:.|:|....:.|. .||:..|
Human   241 DRHWH--HNCFSCARCSTSLVGQGFVPDGDQVLCQ-GCSQAGP 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	8/42 (19%)
		LIM1_Prickle	593..651	CDD:188799	18/59 (31%)
		LIM2_Prickle	656..711	CDD:188802	18/54 (33%)
		LIM3_Prickle	716..774	CDD:188804	19/59 (32%)
FHL3	NP_004459.2	LIM	<5..33	CDD:413332
		LIM1_FHL3	36..94	CDD:188807	3/10 (30%)
		LIM2_FHL3	98..155	CDD:188811	20/81 (25%)
		LIM3_FHL	162..213	CDD:188732	15/51 (29%)
		LIM4_FHL3	221..276	CDD:188818	19/57 (33%)