DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment esn and FHL2

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_001034581.1	Gene:	FHL2 / 2274	HGNCID:	3703	Length:	279	Species:	Homo sapiens

Alignment Length:	185	Identity:	56/185 - (30%)
Similarity:	88/185 - (47%)	Gaps:	10/185 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   593 CKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPR 657
            |:.|::.:..|...:  :..|:.  ||..||:|..|::.:....:..:|...:|...:.:....:
Human   101 CQECKKTIMPGTRKM--EYKGSS--WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQ 161

  Fly   658 CSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCG 722
            |..|.:.|.:...|..| :.||.:.|.|..|..||.|||:..|:...|||.||..::|:.|..|.
Human   162 CVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCT 225

  Fly   723 EVIGVDQG--QMSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSK 775
            ..|....|  .:|.:.:.||  :.||:|..|..||:||.||..|..|.|. .|.|
Human   226 NPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILCP-DCGK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602
		LIM1_Prickle	593..651	CDD:188799	12/57 (21%)
		LIM2_Prickle	656..711	CDD:188802	20/54 (37%)
		LIM3_Prickle	716..774	CDD:188804	20/59 (34%)
FHL2	NP_001034581.1	LIM	<5..33	CDD:413332
		LIM1_FHL2	36..97	CDD:188806
		LIM2_FHL2	101..157	CDD:188810	12/59 (20%)
		LIM3_Fhl2	162..218	CDD:188815	21/56 (38%)
		LIM4_FHL2	221..278	CDD:188817	22/60 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810