Protein Alignment esn and FHL1

DIOPT Version :10

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: NP_001427698.1
• Gene: FHL1 / 2273
• HGNCID: 3702
• Length: 339
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 68/272 - (25%)
• Similarity: 102/272 - (37%)
• Gaps: 58/272 - (21%)

  Fly   584 VRLLSDERPCKGCEEPLSGGDIVVFAQRLGAQLC------------------------------- 617
            |..::::..|..|.:||.|..   :.|:.|...|
Human    14 VGTMAEKFDCHYCRDPLQGKK---YVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNR 75

  Fly   618 -WHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSAC-DEIIFSDECTEAEGRTWHM 680
             ||..||.|:.|...|.:..:..:|..:.|.:.......|:|..| ..|:..|:..|.:|..||.
Human    76 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 140

  Fly   681 KHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQC 745
            ..|.|..|:..:|...:..:....||:.|.:|.||::|..|.:.|  ..|.:::..|.|||  .|
Human   141 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHA--DC 201

  Fly   746 FSCCTCRCSLLGRPFLPRRGTIYCSIACSKG----------EPPTPSDTSSGPQLRPTHRASTSS 800
            |.|.||...|.|:.|.......|| :.|.|.          .|.|...|.|    |.:|..   |
Human   202 FVCVTCSKKLAGQRFTAVEDQYYC-VDCYKNFVAKKCAGCKNPITGKRTVS----RVSHPV---S 258

  Fly   801 QIAKSPRRGGER 812
            :..|.|...|:|
Human   259 KARKPPVCHGKR 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	1/3 (33%)
		LIM1_Prickle	593..651	CDD:188799	17/89 (19%)
		LIM2_Prickle	656..711	CDD:188802	16/55 (29%)
		LIM3_Prickle	716..774	CDD:188804	18/57 (32%)
FHL1	NP_001427698.1	None