DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esn and Fhl4

DIOPT Version :9

Sequence 1:	NP_001260760.1	Gene:	esn / 53557	FlyBaseID:	FBgn0263934	Length:	1134	Species:	Drosophila melanogaster
Sequence 2:	NP_034344.2	Gene:	Fhl4 / 14202	MGIID:	1338765	Length:	279	Species:	Mus musculus

Alignment Length:	219	Identity:	59/219 - (26%)
Similarity:	88/219 - (40%)	Gaps:	41/219 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   590 ERPCKGCEEPLSGGDIVVFAQRLGAQLC--------------------------------WHPGC 622
            |..|..|||.|.|..   :.|:.||..|                                ||..|
Mouse     3 EFKCHHCEESLQGKK---YVQKDGANYCVTCFDSHCANICQECHKPIGADSKEVCYKEQFWHNTC 64

  Fly   623 FVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSAC-DEIIFSDECTEAEGRTWHMKHFACQ 686
            |.||.|.:||....:...|.|:.|.:.......|:|..| .:|...|...|.:|..||...|.|.
Mouse    65 FKCSKCSQLLATETFVAWDKNILCNKCATRVTFPKCKGCLKDIEEGDHNVEYKGSIWHKNCFVCT 129

  Fly   687 ECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTC 751
            .|:..:|.:.:..::...||:.|:|.:|.::|..|.:.|  ..|.:|:..|.||:  :||.|.:|
Mouse   130 NCKDIIGTKNFFPKDEGFYCVTCYDALFTKHCMKCKKPI--TSGGVSYQDQPWHS--ECFVCVSC 190

  Fly   752 RCSLLGRPFLPRRGTIYCSIACSK 775
            ...|.|:.|.......:| :.|.|
Mouse   191 SKELSGQRFTAMDDQYFC-VDCYK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602
		LIM1_Prickle	593..651	CDD:188799	22/89 (25%)
		LIM2_Prickle	656..711	CDD:188802	16/55 (29%)
		LIM3_Prickle	716..774	CDD:188804	16/57 (28%)
Fhl4	NP_034344.2	LIM	<4..32	CDD:295319	10/30 (33%)
		LIM	39..92	CDD:295319	12/52 (23%)
		LIM2_FHL1	100..157	CDD:188808	16/56 (29%)
		LIM3_FHL1	161..213	CDD:188813	17/56 (30%)
		LIM4_FHL1	216..279	CDD:188734
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810