Protein Alignment esn and WTIP

DIOPT Version :9

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: XP_011524754.1
• Gene: WTIP / 126374
• HGNCID: 20964
• Length: 472
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 115/484 - (23%)
• Similarity: 160/484 - (33%)
• Gaps: 125/484 - (25%)

  Fly   379 EAGGTGLTFASHSQR----PESAISQVASTAHLDVPSAASSGSGGSAVSGGSGGAPESAG----- 434
            |||..||:......|    ||.:.....|      |.|:.:||.|    ||.||:..|:|
Human    60 EAGADGLSRGERGPRRAAVPELSAQPAGS------PRASLAGSDG----GGGGGSARSSGISLGY 114

  Fly   435 --RFVSPLQRRHCQPPSHLPLNSVASPLRTASYKSAAAVAGHGFHHSHHQQLDFQRNSQSDDDSG 497
              |..||...|....|...| .||.|        :.::|:..|...|.....||
Human   115 DQRHGSPRSGRSDPRPGPGP-PSVGS--------ARSSVSSLGSRGSAGAYADF----------- 159

  Fly   498 CALEEYTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDE 562
                    :|||..|...|   |..|....|        :.:..|  .|||
Human   160 --------LPPGACPAPAR---SPEPAGPAP--------FPLPAL--PLPP-------------- 189

  Fly   563 ERKELRIFSAQRKREALGRGAVRLLSDERP------CKGCEEPLSGGDIVVFAQRLGAQLCWHPG 621
             .:|....:|:|:.|||.|...|.|.....      |..|...:.|....  .|.:|:  .:|..
Human   190 -GREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQA--CQAMGS--LYHTD 249

  Fly   622 CFVCSVCKELLVDLIYFQRDGNLYCGRHHA----ETQKPRCSACDEIIFSDECTEAEGRTWHMKH 682
            ||.|..|...|....::.....:||.....    :....:||.|..:|. :...:|.|:::|...
Human   250 CFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIM-EMILQALGKSYHPGC 313

  Fly   683 FACQECEHQLGGQRYIMR-EGKPYCLACFDTMFAEYCDYCGEVIGVDQG--------QMSHDGQH 738
            |.|..|...|.|..:.:. |...||:..:.|:||..|..|...|...||        .|..|
Human   314 FRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRD--- 375

  Fly   739 WHATDQCFSCCTCRCSLLGRPFLPRRGTIYC----SIAC-SKGEPPTPSDTSSGPQLRPTHRAST 798
            :|..  |:.|.............|...::.|    |:.| |...||.|      |.|.|   ...
Human   376 YHVA--CYHCEDPGDEARMADSNPLAASLPCMEQLSLGCRSSCVPPLP------PGLSP---CLL 429

  Fly   799 SSQIAKSPRRGGERE--RDPGRKAHHGHP 825
            ..::.:||.....|.  ..||   |..||
Human   430 GLEVPRSPEVLSCRRLLMAPG---HTHHP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	20/95 (21%)
		LIM1_Prickle	593..651	CDD:188799	13/57 (23%)
		LIM2_Prickle	656..711	CDD:188802	15/55 (27%)
		LIM3_Prickle	716..774	CDD:188804	14/70 (20%)
WTIP	XP_011524754.1	LIM1_Ajuba_like	225..278	CDD:188738	13/56 (23%)
		LIM2_Ajuba_like	290..342	CDD:188741	15/52 (29%)
		LIM	350..404	CDD:295319	11/58 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810