Protein Alignment esn and atxn7l1

DIOPT Version :10

• Sequence 1: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Sequence 2: XP_002933154.2
• Gene: atxn7l1 / 100498036
• XenbaseID: XB-GENE-1011002
• Length: 850
• Species: Xenopus tropicalis
• Alignment Length: 828
• Identity: 142/828 - (17%)
• Similarity: 248/828 - (29%)
• Gaps: 307/828 - (37%)

  Fly   387 FASHSQRPESAISQVASTAHLDVPSAASSGSGGSAVSGGSGGAPESAGRFVSP----LQRRHCQP 447
            |.||.:|...::.:.:       ||.|||.|.                  :.|    ::.:.|.
 Frog   117 FQSHCERRHGSMCKPS-------PSPASSPSN------------------IKPSHVQMKPKPCM- 155

  Fly   448 PSHLPLNSVASP-------LRTASYKSAAAVAGHGFHHSHHQQLDFQRNSQSDDDSGC------A 499
            .||.|:||.:.|       |.|::.|...|.                 :|:...|..|      :
 Frog   156 SSHNPVNSNSKPFKAPRDNLLTSNNKQHTAF-----------------SSKVSRDKPCVPVPVVS 203

  Fly   500 LEEYTWVPPGLRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEER 564
            ||:   :|..::.|...:..:.:.:......:|.....:...:...:|....::.....:...||
 Frog   204 LEK---IPNLVKADGANVKMNSVTNSSTTAASSASSLPKQPAVPKTVPQSPEKILNGKGIGTLER 265

  Fly   565 KELRIFSAQRKREALGRGAVRLLSDERPCKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCK 629
            |.                       :...|...:|.         :||..:
 Frog   266 KH-----------------------QNGTKTSNKPY---------KRLSER-------------- 284

  Fly   630 ELLVDLIYFQRDGNLYCGRHHAETQKPRCSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGG 694
                     :.|.|.:||....||:||             ||         :...|:  .|.|..
 Frog   285 ---------EFDPNKHCGVLDPETKKP-------------CT---------RSLTCK--THSLNH 316

  Fly   695 QRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTCRCSLLGRP 759
            :|.:....|.     ||.:.||:.....|      .:::.|.:|..::.:
 Frog   317 RRAVPGRKKQ-----FDILLAEHKARSRE------KEVTKDKEHAPSSRE--------------- 355

  Fly   760 FLPRRGTIYCSIACSKGEPPTPS-DTSSG------PQLRPTHRASTSSQIAKSPRRGGERERDPG 817
                          :....|||: :.|||      |:.:.|..|.:..|.:..||.......:..
 Frog   356 --------------THQSQPTPAQEQSSGVALNSVPEPKVTSPAKSRPQNSALPRPTSANSINSA 406

  Fly   818 RKAHHG----HPKATGSAGDLLERQERQRMEAAGV-----ADLLLGGGVPGMPRPAHPPPIDLTE 873
            ..::|.    .|..:...|||..|......|..||     .|....|        .||.|:....
 Frog   407 SSSNHSAFVPEPPVSSVGGDLASRLSSDEGEVEGVEETEKLDCFYSG--------HHPKPLAFCS 463

  Fly   874 LG-------------------ISLDNIC--------------AGDKSIFGDTQTLTNSMPDMLLS 905
            .|                   .:|:::.              |.|..:......:::|.|..:|.
 Frog   464 FGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPVTHVSSSFPASVLQ 528

  Fly   906 KADDSHSYQSIDKINLNSP-SNSDLTQS---TQELANELELDNEPVRELPHDGYEQLFAN----- 961
            ...:.:|      :.|:|| :||..|.|   |..:...:..|...:...|:     .|::
 Frog   529 PFSNPNS------VYLSSPGTNSRTTSSYMVTSGMLTNMAADTNSLTSHPN-----AFSHATGTL 582

  Fly   962 ---NRNQEHPAEQYDDEQLDNRP------MKEVRFHSVQDTMSRSKSYTDNSNARRRRRRRNQSR 1017
               :...:.|:.......|...|      .|..:...::|..|||:..:.|      |:::.|:.
 Frog   583 NIVDSTFKSPSAVSPVPTLTPSPSQKPSKTKPSKSSKIKDLSSRSEELSGN------RKKKPQTT 641

  Fly  1018 SSSEMQINQTNLRLHNAQTQ--VGTTPLNLLNNLDNCDVASICSTCSSSSSSDMDDYVYRLPARK 1080
            |||    ..::|.|..:.|.  .|:...|                |..:|:|.::.|    .|..
 Frog   642 SSS----TSSSLPLQTSSTSSFSGSHKKN----------------CVLNSNSGLNSY----QATS 682

  Fly  1081 HYGGVRVAYVPNDALAYERKKKMAQDSSLAPGAGNASVGGAPAIMHES 1128
            .|..|.|....|.......|.:       .||..:.|.|.|.:|.|.|
 Frog   683 SYNSVSVHNANNGTSPLSAKLE-------PPGRTSLSGGPADSIKHMS 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	11/101 (11%)
		LIM1_Prickle	593..651	CDD:188799	8/57 (14%)
		LIM2_Prickle	656..711	CDD:188802	8/54 (15%)
		LIM3_Prickle	716..774	CDD:188804	4/57 (7%)
atxn7l1	XP_002933154.2	SCA7	278..339	CDD:462422	21/121 (17%)