DRSC/TRiP Functional Genomics Resources

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Protein Alignment esn and LIMS4

DIOPT Version :9

Sequence 1:NP_001260760.1 Gene:esn / 53557 FlyBaseID:FBgn0263934 Length:1134 Species:Drosophila melanogaster
Sequence 2:NP_001358269.1 Gene:LIMS4 / 100288695 HGNCID:39941 Length:398 Species:Homo sapiens


Alignment Length:358 Identity:77/358 - (21%)
Similarity:112/358 - (31%) Gaps:132/358 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   530 VNSPGEKYRVK-----QLLHQLPP----QDNEVRYCHSLSDEERKELRIFSAQRKREALGRGAVR 585
            |||.||.|..:     |...|.|.    :....:||      |.....:|:              
Human    86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC------EHDFQMLFA-------------- 130

  Fly   586 LLSDERPCKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDL--------------- 635
                  ||  |.:   .|:.::..........|||.||.|.:|:|:|.|:               
Human   131 ------PC--CHQ---CGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 184

  Fly   636 ------------------------IYFQRD------------------------GNLYCGRHHAE 652
                                    :.|:.|                        |.|||...|.:
Human   185 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKDLTADAQELKGELYCLPCHDK 249

  Fly   653 TQKPRCSACDEIIFSDECTEAEGRTWHMKHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEY 717
            ...|.|.||...| ......|.|:.||::||.|.:||....|.|:..|:|..||...::.:|.:.
Human   250 MGVPICGACRRPI-EGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDV 313

  Fly   718 CDYCGEVIGVDQGQMSHDGQHWHATDQCFSCCTCRCSLLGRPFLPRRGTIYCSIACSKGEPPTPS 782
            |.:|..||..|  .:|...:.|..  .||:|.||...|                        |..
Human   314 CFHCNRVIEGD--VVSALNKAWCV--NCFACSTCNTKL------------------------TLK 350

  Fly   783 DTSSGPQLRPTHRASTSSQIAKSPRRGGERERD 815
            |......|:|..:........:..||..:|||:
Human   351 DKFVEIDLKPVCKHCYEKMPEEFKRRLAKRERE 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
esnNP_001260760.1 PET_Prickle 492..588 CDD:193602 13/66 (20%)
LIM1_Prickle 593..651 CDD:188799 19/120 (16%)
LIM2_Prickle 656..711 CDD:188802 20/54 (37%)
LIM3_Prickle 716..774 CDD:188804 13/57 (23%)
LIMS4NP_001358269.1 LIM1_PINCH 72..130 CDD:188717 12/49 (24%)
LIM2_PINCH 133..184 CDD:188718 12/53 (23%)
LIM3_PINCH 197..247 CDD:188719 6/49 (12%)
LIM4_PINCH 253..306 CDD:188720 20/53 (38%)
LIM5_PINCH 314..367 CDD:188721 17/80 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1704
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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