DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dbo and AT1G27420

DIOPT Version :9

Sequence 1:	NP_524989.2	Gene:	dbo / 53556	FlyBaseID:	FBgn0040230	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_174062.1	Gene:	AT1G27420 / 839632	AraportID:	AT1G27420	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	424	Identity:	108/424 - (25%)
Similarity:	158/424 - (37%)	Gaps:	135/424 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 VMESEEFLLLPVGQLVDI--ICSDELNVRSEEQVFNAV-MSWLKYNVAERRQHLAQVLQHVRLPL 265
            |:||....::| |...|:  :|..:: .||..|:.:.| ..|..:   .|.||.|.|
plant     2 VVESSSSPIIP-GLTDDVAELCVSKI-PRSSFQITSQVCRRWRSF---LRSQHFAAV-------- 53

  Fly   266 LSPKFLVGTVGSDLLVRSDEAC-RD----LVDEAKNYL--LLPQERPLMQGPRTRPRKPTRRGEV 323
               :.|.|||...|.|..:..| ||    :.|.:.|.|  :.|...||.:|...   .....|::
plant    54 ---RKLTGTVEEFLCVLMESECGRDVYWEVFDASGNKLGQIPPVPGPLKRGFGV---AVLDGGKI 112

  Fly   324 LFAVGGWC----SG------DAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHD 378
            :| .||:.    ||      .|.|.|..|||..|.|:.:|.|:..|.....|.:|.|||.:.|:.
plant   113 VF-FGGYTEVEGSGINSTTVSASADVYEFDPANNSWRKLAGMNIPRYNFAFAEVNGLLYVIRGYS 176

  Fly   379 GQSY-LNSIERYDPQTNQWS---CDVAPTTSCRTSVGVAVLDGF-------LYAVGGQDGVQCLN 432
            ..:| |::.|.|:|:|||||   |...|           |..||       |||||...     .
plant   177 TDTYSLSNAEVYNPKTNQWSLMHCPNRP-----------VWRGFAFAFSSKLYAVGNGS-----R 225

  Fly   433 HVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPM 497
            .::.||||...|.::                                         |...:||..
plant   226 FIDIYDPKTQTWEEL-----------------------------------------NSEQSVSVY 249

  Fly   498 STRRKHLGCAVFNNYIYAVGGRDDCMELSSAER---YNPLTNTWSPIVAMTSRRSG--VGLAVVN 557
            |       ..|..|.:|       .|:.:...|   ::|..|:||. |.:..|..|  |.|.|.|
plant   250 S-------YTVVRNKVY-------FMDRNMPGRLGVFDPEENSWSS-VFVPPREGGFWVRLGVWN 299

  Fly   558 GQLYAVGGFDGSAYLKTIEVYD---PETNQWRLC 588
            .::.......|...|    :||   .:.::||:|
plant   300 NKVLLFSRVCGHETL----MYDLDKEKGSKWRVC 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558
		PHA03098	69..587	CDD:222983	106/421 (25%)
		KELCH repeat	359..403	CDD:276965	18/47 (38%)
		KELCH repeat	407..451	CDD:276965	13/50 (26%)
		KELCH repeat	454..497	CDD:276965	3/42 (7%)
		KELCH repeat	501..545	CDD:276965	10/46 (22%)
		KELCH repeat	548..593	CDD:276965	12/46 (26%)
AT1G27420	NP_174062.1	F-box	9..50	CDD:395521	11/45 (24%)
		PHA03098	<81..286	CDD:222983	69/280 (25%)
		KELCH repeat	100..153	CDD:276965	16/56 (29%)
		KELCH repeat	157..202	CDD:276965	18/44 (41%)
		KELCH repeat	205..242	CDD:276965	13/82 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960