DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dbo and AFR

DIOPT Version :9

Sequence 1:	NP_524989.2	Gene:	dbo / 53556	FlyBaseID:	FBgn0040230	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_565572.1	Gene:	AFR / 816990	AraportID:	AT2G24540	Length:	372	Species:	Arabidopsis thaliana

Alignment Length:	192	Identity:	50/192 - (26%)
Similarity:	79/192 - (41%)	Gaps:	48/192 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 GFLYAVGGQDGVQCLNHVER----YDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGS---DG 474
            |.|:.:||.|       |.|    |....|:||.::||.:.|.......:.|.:.|:|||   :|
plant   134 GKLFVLGGGD-------VNRSAVVYTALTNRWSCISPMMSPRTYFVSGNVNGKIMAVGGSVGGNG 191

  Fly   475 QCPLNTVERYDPRHNKWVAVS--PMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSA--------- 528
            :. ...||.|||.::.|..|.  ||          |...|..||.|::.|:....|
plant   192 EA-TTEVESYDPDNDTWTVVKKLPM----------VLAKYDSAVIGKEMCVTEGWAWPFMFPPMG 245

  Fly   529 ERYNPLTNTWSPIV-AMTSRRSGVGLAVVNGQLYAV---GGFDGSAYLKTIEVYDPETNQWR 586
            :.|:....||..:. .|....:||.: |:..:|:.:   |.|       .::||..:.:.||
plant   246 QVYDSDEGTWREMSGGMKEGWTGVSV-VIRDRLFVISEHGDF-------PMKVYCSDDDTWR 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558
		PHA03098	69..587	CDD:222983	50/192 (26%)
		KELCH repeat	359..403	CDD:276965
		KELCH repeat	407..451	CDD:276965	12/37 (32%)
		KELCH repeat	454..497	CDD:276965	14/47 (30%)
		KELCH repeat	501..545	CDD:276965	10/53 (19%)
		KELCH repeat	548..593	CDD:276965	10/42 (24%)
AFR	NP_565572.1	F-box	27..72	CDD:279040
		Kelch_1	167..214	CDD:279660	14/47 (30%)
		KELCH repeat	168..214	CDD:276965	14/46 (30%)
		KELCH repeat	217..259	CDD:276965	9/41 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960