DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbo and SKIP6

DIOPT Version :9

Sequence 1:	NP_524989.2	Gene:	dbo / 53556	FlyBaseID:	FBgn0040230	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_565522.1	Gene:	SKIP6 / 816731	AraportID:	AT2G21950	Length:	372	Species:	Arabidopsis thaliana

Alignment Length:	360	Identity:	87/360 - (24%)
Similarity:	123/360 - (34%)	Gaps:	111/360 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 SGDAIASVERFDPQTNDWKMVAPMSKR-----------RCGVGVAVL----------NDLLYA-- 373
            |||.       .|:|.....:.|:...           ||...:..|          :.||||
plant     7 SGDE-------PPETKSPAQLIPLLSEDVALSCLARVPRCHYPILSLVSKTFRSLPTSPLLYATR 64

  Fly   374 --VGGHDGQSYLNSIERYDPQTNQ-W-------------SCDVAPTTSCRTS--VGVA--VLDGF 418
              ||..:...|:  ..|..|::.. |             |..:.|..||.:.  ||.|  |:|..
plant    65 ALVGATENILYV--AIRIPPESGACWFTLLHRTLSNSTNSKMLVPIPSCPSPSLVGSAYVVVDSE 127

  Fly   419 LYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQC------- 476
            :|.:||.......:.|...|.:.:.|.:|:.|...|...|..|:.|.:|.|||    |
plant   128 IYVIGGSIRDVPSSSVWVLDCRFHTWRRVSNMRVGREFAAAGVIDGKIYVIGG----CVVDNWAR 188

  Fly   477 PLNTVERYDPRHNKW--VAVSPMSTRRKHL-GCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTW 538
            .:|..|.:|.:...|  ||...|..|.|.: ..||....:||:..|:..:       |.|....|
plant   189 SINWAEMFDIKTQTWEPVASPGMEVREKWMHASAVMEGKVYAMADRNGVV-------YEPKEKKW 246

  Fly   539 SPIVAMTSRRSGVG----LAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWR-----------LC 588
            .    |..:|..:|    ..|:...||.   :|   ||..|..|||:...||           ||
plant   247 E----MPEKRLDLGWRGRACVIENILYC---YD---YLGKIRGYDPKERIWRELKGVESLPKFLC 301

  Fly   589 GCMNYRRLG---------GGVGVMRAPQTENYMWC 614
            |.....|.|         .|.|..|..:    :||
plant   302 GATMANRGGKLTVLWEGKAGSGGSRRME----IWC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558
		PHA03098	69..587	CDD:222983	77/322 (24%)
		KELCH repeat	359..403	CDD:276965	14/71 (20%)
		KELCH repeat	407..451	CDD:276965	12/47 (26%)
		KELCH repeat	454..497	CDD:276965	15/51 (29%)
		KELCH repeat	501..545	CDD:276965	9/44 (20%)
		KELCH repeat	548..593	CDD:276965	17/59 (29%)
SKIP6	NP_565522.1	F-box	21..64	CDD:279040	8/42 (19%)
		Kelch_1	117..160	CDD:279660	12/42 (29%)
		KELCH repeat	122..159	CDD:276965	9/36 (25%)
		muta_rot_YjhT	153..>352	CDD:274641	54/205 (26%)
		KELCH repeat	163..212	CDD:276965	15/52 (29%)
		Kelch_1	163..210	CDD:279660	15/50 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960