DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbo and AT2G21680

DIOPT Version :9

Sequence 1:	NP_524989.2	Gene:	dbo / 53556	FlyBaseID:	FBgn0040230	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_179761.4	Gene:	AT2G21680 / 816706	AraportID:	AT2G21680	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	319	Identity:	67/319 - (21%)
Similarity:	114/319 - (35%)	Gaps:	93/319 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 VGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAI 336
            |.|:|||:.|........|:::..    :...:|:..|         ||||
plant   138 VVTIGSDIYVIGGRVGEKLLEDVG----VGYNKPISGG---------RRGE-------------- 175

  Fly   337 ASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQW-SCDV 400
            .|:.                                  |||.|:..::.:...:.:.::: |...
plant   176 TSIR----------------------------------GGHAGERRISDVTHINCRFHEYRSLPS 206

  Fly   401 APTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGF 465
            .....||.:.|  |:||.:|.:||:. |:..:.||.:|.|:..||.|........|     .|.|
plant   207 MKMARCRAAAG--VIDGKIYVIGGRK-VRTSDWVEVFDLKKQSWSSVPGPYPEAFG-----RGEF 263

  Fly   466 L-YAIGGSDGQC--PLNTVERYDPRHNKWVAVS--PMSTRRKHLGCAV------FNNYIYAVGGR 519
            | ||:......|  ....:..|||:.:||.:.:  |:|.......|.|      .|..:|.:|.
plant   264 LTYAVMKEKIYCLDLTRNIHIYDPKESKWESWTHGPLSASWNDSSCVVDNLLFCINTSVYFLGW- 327

  Fly   520 DDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVY 578
                   ..:.|:|...||..:..:....:. || .|:|  |.:..|.|...:.:.:|:
plant   328 -------PIKIYDPEKKTWFYLQGLQGFPAN-GL-FVDG--YKMANFGGKLVILSADVH 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558
		PHA03098	69..587	CDD:222983	67/319 (21%)
		KELCH repeat	359..403	CDD:276965	5/44 (11%)
		KELCH repeat	407..451	CDD:276965	16/43 (37%)
		KELCH repeat	454..497	CDD:276965	12/47 (26%)
		KELCH repeat	501..545	CDD:276965	9/49 (18%)
		KELCH repeat	548..593	CDD:276965	8/31 (26%)
AT2G21680	NP_179761.4	F-box	42..76	CDD:395521
		PHA03098	<85..339	CDD:222983	57/277 (21%)
		KELCH repeat	135..207	CDD:276965	19/129 (15%)
		Kelch_1	210..251	CDD:396078	16/43 (37%)
		KELCH repeat	211..255	CDD:276965	17/46 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910