| Sequence 1: | NP_524989.2 | Gene: | dbo / 53556 | FlyBaseID: | FBgn0040230 | Length: | 623 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_065917.1 | Gene: | KLHL1 / 57626 | HGNCID: | 6352 | Length: | 748 | Species: | Homo sapiens |
| Alignment Length: | 623 | Identity: | 257/623 - (41%) |
|---|---|---|---|
| Similarity: | 375/623 - (60%) | Gaps: | 27/623 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3 DLPG---SGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEK------HPKVT 58
Fly 59 LTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAM 123
Fly 124 ELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRE 188
Fly 189 LLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQH 253
Fly 254 LAQVLQHVRLPLLSPKFLVGTVGSDL----LVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRP 314
Fly 315 RKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDG 379
Fly 380 QSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKW 444
Fly 445 SKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVF 509
Fly 510 NNYIYAVGGRD-----DCME-LSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDG 568
Fly 569 SAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAP 606 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dbo | NP_524989.2 | BTB_POZ_KLHL20_KLEIP | 49..176 | CDD:349558 | 55/132 (42%) |
| PHA03098 | 69..587 | CDD:222983 | 236/527 (45%) | ||
| KELCH repeat | 359..403 | CDD:276965 | 18/43 (42%) | ||
| KELCH repeat | 407..451 | CDD:276965 | 23/43 (53%) | ||
| KELCH repeat | 454..497 | CDD:276965 | 20/42 (48%) | ||
| KELCH repeat | 501..545 | CDD:276965 | 18/49 (37%) | ||
| KELCH repeat | 548..593 | CDD:276965 | 21/44 (48%) | ||
| KLHL1 | NP_065917.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 22..93 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 151..182 | 5/30 (17%) | |||
| PHA03098 | 206..728 | CDD:222983 | 235/529 (44%) | ||
| Kelch 1 | 460..506 | 17/45 (38%) | |||
| KELCH repeat | 496..539 | CDD:276965 | 18/43 (42%) | ||
| Kelch 2 | 507..553 | 18/46 (39%) | |||
| KELCH repeat | 543..587 | CDD:276965 | 23/43 (53%) | ||
| Kelch 3 | 555..600 | 23/44 (52%) | |||
| KELCH repeat | 590..633 | CDD:276965 | 20/42 (48%) | ||
| Kelch 4 | 601..647 | 20/45 (44%) | |||
| KELCH repeat | 637..687 | CDD:276965 | 18/49 (37%) | ||
| Kelch 5 | 649..700 | 18/50 (36%) | |||
| KELCH repeat | 690..734 | CDD:276965 | 21/43 (49%) | ||
| Kelch 6 | 701..747 | 23/45 (51%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4441 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D312716at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000036 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X9 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.820 | |||||