Protein Alignment dbo and klhl2

DIOPT Version :9

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_021329567.1
• Gene: klhl2 / 567966
• ZFINID: ZDB-GENE-090312-193
• Length: 590
• Species: Danio rerio
• Alignment Length: 559
• Identity: 256/559 - (45%)
• Similarity: 349/559 - (62%)
• Gaps: 8/559 - (1%)

  Fly    53 KHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRD 117
            :|.|.....:|.||....||||.:.....:|.||||:|:|.|.||.||||||:.||||.:|.|::
Zfish    34 RHMKKAFRIMNELRSQSVLCDVTIIAEDVEIAAHRVVLAAGSPYFHAMFTGEMTESRQKKVRIKE 98

  Fly   118 IDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFAD 182
            ||...:.:|||:.|||.|.|.|.|||.|||||.||||.|::..|||||..||.||||||||||||
Zfish    99 IDGWTLGMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQEVKKACCEFLITQLHPTNCLGIRAFAD 163

  Fly   183 THSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNV 247
            .|:|.|||.:|:.:.:.:|.||::|||||.|.:.|:..:|.||:|.:.|||:||.||::|:.::.
Zfish   164 LHACTELLNLANTYAEQHFSEVVQSEEFLNLGMDQVCSLIASDKLTIPSEEKVFEAVIAWVMHDK 228

  Fly   248 AERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLP-QERPLMQGPR 311
            ..|::|||.:::||||||||.::||..|..:.||::..||:|.:.||..|.||| .:|.:|:..|
Zfish   229 DVRQEHLAHLMEHVRLPLLSREYLVQRVEEETLVKNSSACKDYLIEAMKYHLLPADQRSMMKTIR 293

  Fly   312 TRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGG 376
            ||.|.|....:|:..|||. :..||.|||.:|.:...|..||.:..|||..||..:..::|||||
Zfish   294 TRVRTPISYPKVMMVVGGQ-APKAIRSVECYDFEEERWFQVAELPSRRCRAGVVFMGGVVYAVGG 357

  Fly   377 HDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKE 441
            .:|...:.:::.|||..::|.| |:.....|:::|.|.|.|.||||||.||...|..||.|:.|.
Zfish   358 FNGSLRVRTVDAYDPVKDEWCC-VSSMQDRRSTLGCAFLSGLLYAVGGFDGSTGLATVEAYNAKA 421

  Fly   442 NKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDG---QCPLNTVERYDPRHNKWVAVSPMSTRRKH 503
            |:|..|.||.|||..|.|.|:||.|||:||.||   || |:|||.|:|..|:|...:.|.|||..
Zfish   422 NEWFHVNPMNTRRSSVGVGVVGGLLYAVGGYDGATRQC-LSTVEAYNPNTNEWSYTAEMGTRRSG 485

  Fly   504 LGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDG 568
            .|..|....:|||||.|..:...|.|.::|.||||..:..|...|...|:..::..||.:||.||
Zfish   486 AGVGVLKGLLYAVGGHDGPLVRKSCEVFDPATNTWKQVADMNMCRRNAGVCALSNLLYVIGGDDG 550

  Fly   569 SAYLKTIEVYDPETNQWRLC-GCMNYRRLGGGVGVMRAP 606
            |..|.::|.|:|.|::|.|. .||:..|...||.|:..|
Zfish   551 SCNLASVEFYNPNTDKWTLLPTCMSTGRSYAGVTVIDKP 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	66/122 (54%)
		PHA03098	69..587	CDD:222983	243/521 (47%)
		KELCH repeat	359..403	CDD:276965	16/43 (37%)
		KELCH repeat	407..451	CDD:276965	22/43 (51%)
		KELCH repeat	454..497	CDD:276965	23/45 (51%)
		KELCH repeat	501..545	CDD:276965	16/43 (37%)
		KELCH repeat	548..593	CDD:276965	18/45 (40%)
klhl2	XP_021329567.1	BTB	53..569	CDD:333434	242/518 (47%)
		KELCH repeat	340..383	CDD:276965	16/43 (37%)
		KELCH repeat	483..527	CDD:276965	16/43 (37%)
		KELCH repeat	530..571	CDD:276965	16/40 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59391
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000036
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010