Protein Alignment dbo and klhl36

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_073785212.1
• Gene: klhl36 / 553604
• ZFINID: ZDB-GENE-050522-324
• Length: 645
• Species: Danio rerio
• Alignment Length: 591
• Identity: 178/591 - (30%)
• Similarity: 284/591 - (48%)
• Gaps: 52/591 - (8%)

  Fly    44 PARLSHTSEKH-----PKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTG 103
            |.|||.:|:.:     ....|..||..|:|.::|||||....::|.|||.:|:..|.||.||||.
Zfish    52 PHRLSESSKVYRWADQANNLLQGLNEQRQHGQMCDVVLVADDQRIPAHRALLAVSSPYFQAMFTL 116

  Fly   104 ELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQ 168
            .:.|..::|:.:.......::.:|||.|:.::.::..|:..:|..|.|||:.:..|.||::|:::
Zfish   117 GMREEHESEIELVGASYVGVKAVIDFLYSGNLPLDGGNIDYVLETAHLLQVWQAVDFCCQYLEKE 181

  Fly   169 LDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLL-LPVGQLVDIICSDELNVRSE 232
            :...|.|.::..|..:|...|....|:|...:|..:..:.|||. :.:.:|...:.|:::...:|
Zfish   182 VREDNYLYLQELALLYSLDRLDAFIDRFILKHFSTLAITSEFLQDVRMFKLCAYLSSEQVQCLNE 246

  Fly   233 EQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDL--LVRSDEACRDLVDEAK 295
            |.:|.....|||.. .||.:...|:|.::|..|:....|...|..:|  |:..|.:|:.||:||.
Zfish   247 ETLFEVAFKWLKQK-PERLEFALQLLSNIRFALIPFYLLKYYVLPNLHSLLPLDTSCKVLVEEAI 310

  Fly   296 NYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCS--GDAI-ASVERFDPQTNDW----KMVA 353
            :|......:|:||..||..|...   |.|..:||..|  |:.: |.|...|.:...|    ||.|
Zfish   311 DYHRKLSAQPVMQTQRTGLRGGV---ECLLLLGGEVSERGEGLSAEVCWLDEEAGKWVEETKMPA 372

  Fly   354 PMSKRRCGVGVAVLNDLLYAVGG-----HDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVA 413
            |.| :.|   ||||...::..||     :.|.|..:.:.||||:...| ...||....|....:.
Zfish   373 PRS-QHC---VAVLGGFIFTAGGSCSPDNGGDSASDMLYRYDPRRCHW-IKGAPMNQRRVDFYLG 432

  Fly   414 VLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQC-P 477
            .:...|.||||::....|:.||.|.|.::.|:.||.:.....|.|..:..|.:|..||.|.|. |
Zfish   433 TMGECLIAVGGRNDSGPLSSVEVYHPADDHWTYVAELPKFTYGHAGTIHKGIVYISGGHDYQIGP 497

  Fly   478 L-NTVERYDPR-HNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRD---DCME---LSSAERYNPL 534
            . :.:..|||: .:.|.....|...|.....|...:.|||:||.|   |.||   :...|.::|.
Zfish   498 YRHDMLSYDPKTADAWNECQAMILARGWHSMASLEDRIYAIGGSDDHEDSMERFDVLEVEAFDPQ 562

  Fly   535 TNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSA--YLKTIEVYDPETNQWRL---------- 587
            ||.|:.|..:....|..||||:|.::|.:||:....  :.:..:|:||:..||.|
Zfish   563 TNQWTMIAPLRYASSEAGLAVLNRKIYVLGGYSWETMDFSQGTQVFDPDKEQWTLGPNLPKHIAG 627

  Fly   588 --CGCM 591
              |.|:
Zfish   628 PSCVCL 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	40/131 (31%)
		PHA03098	69..587	CDD:222983	165/543 (30%)
		KELCH repeat	359..403	CDD:276965	15/48 (31%)
		KELCH repeat	407..451	CDD:276965	14/43 (33%)
		KELCH repeat	454..497	CDD:276965	13/45 (29%)
		KELCH repeat	501..545	CDD:276965	17/49 (35%)
		KELCH repeat	548..593	CDD:276965	17/58 (29%)
klhl36	XP_073785212.1	None