Protein Alignment dbo and klhl20

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_998166.2
• Gene: klhl20 / 406274
• ZFINID: ZDB-GENE-040426-1935
• Length: 591
• Species: Danio rerio
• Alignment Length: 572
• Identity: 462/572 - (80%)
• Similarity: 513/572 - (89%)
• Gaps: 0/572 - (0%)

  Fly    42 PSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELE 106
            |.|||:.:.|:|||:.||..:|:||:|||||||||.||.:||:||||||||||.||.|||||||.
Zfish    20 PQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELA 84

  Fly   107 ESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDP 171
            |||||||.||||||.||||||||.||:.:.|||.||||||||||||||.|||:.|||||||||||
Zfish    85 ESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDP 149

  Fly   172 TNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVF 236
            :||||||||||||||||||||||||||||||||||||||:|||..||:|||.|||||||||||||
Zfish   150 SNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVF 214

  Fly   237 NAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLP 301
            ||||:|:||::.|||..|.|||||||||||||||||||||||.|::|||.|||||||||||||||
Zfish   215 NAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLP 279

  Fly   302 QERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAV 366
            ||||||||||||||||.|.||||||||||||||||:||||:|||||:|:|||.||||||||||:|
Zfish   280 QERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSV 344

  Fly   367 LNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCL 431
            |:|||||||||||.|||||:|||||:|||||.|||||::||||||||||.|:||||||||||.||
Zfish   345 LDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCL 409

  Fly   432 NHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSP 496
            |.|||||||||||::||.|:|||||||||||||||||:|||||..||||||||:|:.|:|..|:|
Zfish   410 NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVAP 474

  Fly   497 MSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLY 561
            |.||||||||||:.:.||:||||||..||||||||||.||.|||:|||||||||||||||||||.
Zfish   475 MGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLM 539

  Fly   562 AVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMW 613
            |||||||:.||||||||||:.|.|||.|.||||||||||||::....|:::|
Zfish   540 AVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	97/126 (77%)
		PHA03098	69..587	CDD:222983	431/517 (83%)
		KELCH repeat	359..403	CDD:276965	37/43 (86%)
		KELCH repeat	407..451	CDD:276965	36/43 (84%)
		KELCH repeat	454..497	CDD:276965	32/42 (76%)
		KELCH repeat	501..545	CDD:276965	33/43 (77%)
		KELCH repeat	548..593	CDD:276965	36/44 (82%)
klhl20	NP_998166.2	None