Protein Alignment dbo and ivns1abpa

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_954973.2
• Gene: ivns1abpa / 387591
• ZFINID: ZDB-GENE-031222-2
• Length: 643
• Species: Danio rerio
• Alignment Length: 639
• Identity: 187/639 - (29%)
• Similarity: 307/639 - (48%)
• Gaps: 94/639 - (14%)

  Fly    58 TLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENA 122
            |:.::|.||::.:.|||.|.|.|.::.|||.:|:.||.|...:|..:||....:.|...|:|..|
Zfish    18 TVAKMNALRKNGQFCDVRLQVCGHELMAHRAVLACCSPYLFEIFNSDLEPHGISHVKFEDLDPEA 82

  Fly   123 MELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCR 187
            :|:|:::.|||.:..::..|:.:..||..|::..::.||.::|..::|..:.:..|.||......
Zfish    83 VEILLNYAYTAQLKADKELVKEVYSAAKRLKMDRVKQICGDYLLSKMDSQSAISYRNFASCMGDG 147

  Fly   188 ELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQ 252
            .||...|.:.|.:..||.|.|:||.||..:| :::..|.|.:.|..::::.|:.|::.::.|..:
Zfish   148 RLLGKIDSYIQEHLLEVSEQEDFLKLPRLKL-EVMLEDNLTLPSNGKLYSKVIGWVQRSLWENGE 211

  Fly   253 HLAQVLQHVRLPLLSP--KFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERP---------- 305
            .|.::::.|:....|.  |.|.|:    ||    :...::.....:::...|::|
Zfish   212 PLERLMEEVQTLYYSADHKLLDGS----LL----DGQAEVFGTEDDHIQFVQKKPPRENVHRQLS 268

  Fly   306 ------LMQGPRTRP----------RKPTRRGEVLFAV--GGWCSGDAIASVERFDPQTNDW--- 349
                  |..|....|          .|.|....:..||  |..|   .|....|..||.:..
Zfish   269 TSSSGSLSPGSTKHPCKQEWKYIASEKTTNNTYLCLAVLNGMLC---VIFLHGRSSPQASPSATP 330

  Fly   350 ------------------KMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQW 396
                              |:::||...|.|:|:|.|||.|.|.||::.:..|.::|.|:.:||.|
Zfish   331 CLTKSLSFEGQPLEEEPDKLLSPMHYARSGLGIASLNDQLIAAGGYNREECLRTVECYNIKTNSW 395

  Fly   397 SCDVAPTTSCRTSVGVAVLDGFLYAVGGQDG----VQCLNHVERYDPKENKWSKVAPMTTRRLGV 457
            :. :||..:.|....:|||.|.||.:||.:|    :.|   .|.|:|..::|::|..:.|.|...
Zfish   396 TF-IAPMRTPRARFQMAVLMGQLYVMGGSNGHSDELSC---GETYNPNADEWTQVPELRTNRCNA 456

  Fly   458 AVAVLGGFLYAIGGSD--GQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRD 520
            .|..|...||.:||||  ||..|...:.:||....|...:|::.||........:.::|.:||.:
Zfish   457 GVCSLNNKLYVVGGSDPCGQKGLKNCDVFDPISKAWTNCAPLNIRRHQAAVCELDGFMYVIGGAE 521

  Fly   521 DCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQW 585
            ....|:|.|||||..|||:.|.:|...|.|.|:||..|:|:.|||||||..|:.:|:|||..|:|
Zfish   522 SWNCLNSVERYNPENNTWTLIASMNIARRGAGVAVYEGKLFVVGGFDGSHALRCVEMYDPVRNEW 586

  Fly   586 RLCGCMNYRRLGGGVGVMR---------------------APQTENYMWCENSF 618
            |:.|.||..|...|..|:.                     .|:||.:..|.::|
Zfish   587 RMLGSMNSPRSNAGAAVLNDVIYAIGGFDGNDFLNSVEAYNPKTEEWSTCADAF 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	37/117 (32%)
		PHA03098	69..587	CDD:222983	171/574 (30%)
		KELCH repeat	359..403	CDD:276965	18/43 (42%)
		KELCH repeat	407..451	CDD:276965	16/47 (34%)
		KELCH repeat	454..497	CDD:276965	15/44 (34%)
		KELCH repeat	501..545	CDD:276965	15/43 (35%)
		KELCH repeat	548..593	CDD:276965	24/44 (55%)
ivns1abpa	NP_954973.2	BTB_POZ_NS1BP	14..137	CDD:349615	37/118 (31%)
		BACK_NS1BP_IVNS1ABP	129..225	CDD:350577	25/96 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..282		3/24 (13%)
		NanM	351..613	CDD:442289	99/265 (37%)
		KELCH repeat	358..401	CDD:276965	18/43 (42%)
		Kelch 1	369..415		16/46 (35%)
		KELCH repeat	405..450	CDD:276965	16/47 (34%)
		Kelch 2	416..463		15/49 (31%)
		KELCH repeat	453..498	CDD:276965	15/44 (34%)
		Kelch 3	465..512		15/46 (33%)
		KELCH repeat	502..545	CDD:276965	15/42 (36%)
		Kelch 4	513..559		20/45 (44%)
		KELCH repeat	549..593	CDD:276965	23/43 (53%)
		Kelch 5	560..606		22/45 (49%)
		Kelch_1	595..638	CDD:396078	7/42 (17%)
		KELCH repeat	596..638	CDD:276965	7/41 (17%)
		Kelch 6	608..643		5/33 (15%)