Protein Alignment dbo and Klhl28

DIOPT Version :9

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001100205.1
• Gene: Klhl28 / 299103
• RGDID: 1311326
• Length: 571
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 244/571 - (42%)
• Similarity: 343/571 - (60%)
• Gaps: 28/571 - (4%)

  Fly    45 ARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESR 109
            |.|:|.   |.:..|..||:||:|.||||::|.||..||.||:|:|::.|.||.|||||.|.|..
  Rat    11 ANLTHL---HSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE 72

  Fly   110 QTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNC 174
            .:||..:.|||.|::.::::.||..:.:.:..|::|||||.|||:..:...||.||:.||||.||
  Rat    73 NSEVEFQCIDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCTFLESQLDPGNC 137

  Fly   175 LGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAV 239
            :||..||:|:.|.:|...|.||...||:.|.::|||..|..|.|.:|:.:|.|||.:||.||.|:
  Rat   138 IGISRFAETYGCHDLYLAATKFICQNFESVCQTEEFFELTHGDLDEIVSNDCLNVATEETVFYAL 202

  Fly   240 MSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQER 304
            .||:||:|.||:::|||:|..|||||||.|||.....::.|:|.|..|:.|::||..|..:|:.|
  Rat   203 ESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHFMPEHR 267

  Fly   305 -----PLMQGPRTRPRKPTRRGEVLFAVGGWCSG--DAIASVERFDPQTNDWKMVAPMSKRRCGV 362
                 .||..||..|:       ||.|||| .||  ..:.|||.:.||.:.|..:||::..|...
  Rat   268 LSHQTVLMTRPRCAPK-------VLCAVGG-KSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEF 324

  Fly   363 GVAVLNDLLYAVGGHDG--------QSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFL 419
            |:.||:..:|.:||.:.        :.:.||:|.::|.||.|: .:......|:::||.||.|.:
  Rat   325 GICVLDQKVYVIGGIETSVRPGVTVRKHENSVECWNPDTNTWT-SLERMNESRSTLGVVVLAGEV 388

  Fly   420 YAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERY 484
            ||:||.||...|..||:|.||..:|..||||||.|...|.|||.|.:|||||. |...:|:||||
  Rat   389 YALGGYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMIYAIGGY-GPAHMNSVERY 452

  Fly   485 DPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRS 549
            ||..:.|..|:.|:.:|.|.|..|...:|:.|||.:....|||.|||:|..|.|:....|...|:
  Rat   453 DPSKDSWETVASMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRT 517

  Fly   550 GVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGV 600
            |||.||::..||.|||..||:||.|::.|||.::.|.....|.|.|...|:
  Rat   518 GVGAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	58/126 (46%)
		PHA03098	69..587	CDD:222983	230/532 (43%)
		KELCH repeat	359..403	CDD:276965	14/51 (27%)
		KELCH repeat	407..451	CDD:276965	22/43 (51%)
		KELCH repeat	454..497	CDD:276965	21/42 (50%)
		KELCH repeat	501..545	CDD:276965	17/43 (40%)
		KELCH repeat	548..593	CDD:276965	21/44 (48%)
Klhl28	NP_001100205.1	PHA03098	35..553	CDD:222983	227/527 (43%)
		KELCH repeat	321..372	CDD:276965	14/51 (27%)
		KELCH repeat	376..419	CDD:276965	21/42 (50%)
		KELCH repeat	423..465	CDD:276965	21/42 (50%)
		KELCH repeat	469..513	CDD:276965	17/43 (40%)
		KELCH repeat	516..559	CDD:276965	20/42 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4441
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59391
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830