Protein Alignment dbo and Ipp

DIOPT Version :9

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001100149.2
• Gene: Ipp / 298439
• RGDID: 1306299
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 579
• Identity: 214/579 - (36%)
• Similarity: 321/579 - (55%)
• Gaps: 30/579 - (5%)

  Fly    48 SHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTE 112
            |.:|:||.::.|.::|.:|..:..|||.|.||......||::|:|.|.||.|:|||.::||.:..
  Rat    13 SFSSDKHAQLILAQMNKMRTGQHFCDVQLQVGKETFQVHRLVLAASSPYFAALFTGGMKESSKDV 77

  Fly   113 VTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGI 177
            |.|..::....:||:||.||..:.:..||||.|:.||.:|||.|:.::||:|||.|:||.||:|:
  Rat    78 VQILGVEAGIFQLLLDFIYTGLVNIAVSNVQELIVAADMLQLTEVVNLCCDFLKGQIDPQNCIGL 142

  Fly   178 RAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSW 242
            ..|::..:|.:||...:.:...:|.||...||||.|...||:.|:.|:||::..|.|||.|.|.|
  Rat   143 FQFSEQIACHDLLEFTENYIHVHFLEVHSGEEFLALTKDQLIRILRSEELSIEDEYQVFLAAMQW 207

  Fly   243 LKYNVAERRQHLAQVLQHVRLPLLSP----KFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQE 303
            :..::.:||:|:.:||..||.|||..    |::.|....:|.|......::..:..|:    |:|
  Rat   208 ILKDLGKRRKHVVEVLDPVRFPLLPSQRLLKYIEGVSDFNLRVALQTLLKEYCEVCKS----PKE 268

  Fly   304 R---PLMQGPRTRPRKPTRRGEVLFAVGG--------WCSGDAIASVERFDPQTNDWKMVAPMSK 357
            .   ..:|..:.||||..|:  .|:||||        |....|::.|||||..:..|..|:.:.:
  Rat   269 NKFCSFLQTSKARPRKKARK--YLYAVGGYTRLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQ 331

  Fly   358 RRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAV 422
            .|||:|||||..::||:||.......:..|.|||.|.||: .||.....|..:||.|..|.:||:
  Rat   332 ARCGLGVAVLGGMVYAIGGEKDSMIFDCTECYDPVTKQWT-TVASMNHPRCGLGVCVCYGAIYAL 395

  Fly   423 GGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGG-SDGQCPLNTVERYDP 486
            ||..|.:..:.:||:||.||||..|..|...|.......:.|.:||:|| |:....|.:.|.|||
  Rat   396 GGWVGAEIGDTIERFDPDENKWEVVGNMAVSRYYFGCCEMQGLIYAVGGISNEGLELRSFEVYDP 460

  Fly   487 RHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCME-LSSAERYNPLTNTWSPIVAMTSRRSG 550
            ...:|..:.||.|||.:||.|..|:.|||:||.::..: |.:.|:|:.....|..:.:|...|:|
  Rat   461 LSKRWSPLPPMGTRRAYLGVAALNDCIYAIGGWNETQDALHTVEKYSFEEEKWIEVASMKVPRAG 525

  Fly   551 VGLAVVNGQLYAVGG------FDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVM 603
            :.:..|||.||..||      |.....|.::|||:|.::.|...|.|...|..|||.|:
  Rat   526 MCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEIGNMITSRCEGGVAVL 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	54/126 (43%)
		PHA03098	69..587	CDD:222983	200/540 (37%)
		KELCH repeat	359..403	CDD:276965	21/43 (49%)
		KELCH repeat	407..451	CDD:276965	19/43 (44%)
		KELCH repeat	454..497	CDD:276965	13/43 (30%)
		KELCH repeat	501..545	CDD:276965	14/44 (32%)
		KELCH repeat	548..593	CDD:276965	18/50 (36%)
Ipp	NP_001100149.2	BTB_POZ_KLHL27_IPP	17..141	CDD:349565	53/123 (43%)
		PHA03098	34..575	CDD:222983	202/547 (37%)
		KELCH repeat	333..376	CDD:276965	21/43 (49%)
		KELCH repeat	380..424	CDD:276965	19/43 (44%)
		KELCH repeat	427..473	CDD:276965	15/45 (33%)
		KELCH repeat	475..520	CDD:276965	14/44 (32%)
		KELCH repeat	523..574	CDD:276965	18/50 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4441
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	1	1.000	-	-		FOG0000036
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820