Protein Alignment dbo and LOC1281663

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_061497908.1
• Gene: LOC1281663 / 1281663
• VectorBaseID: AGAMI1_004119
• Length: 675
• Species: Anopheles gambiae
• Alignment Length: 624
• Identity: 265/624 - (42%)
• Similarity: 363/624 - (58%)
• Gaps: 35/624 - (5%)

  Fly     9 STAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCD 73
            |:|..|.:.||.....|.|...|||......|          ...|..|.|..:....:..:|||
Mosquito    13 SSASVRASLVTDESHFSLASLNSSVSQDEFFR----------CRDHSDVVLKRMQDYLQSEKLCD 67

  Fly    74 VVL--NVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHII 136
            |||  .|.||:|.|||::|||.|:||.|||||:|.||:|.|:|::::..:|:..||.:|||..|.
Mosquito    68 VVLIAGVDGRRIPAHRLVLSASSAYFSAMFTGQLRESQQEEITLQEVSGDALNSLIQYCYTGAIE 132

  Fly   137 VEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNF 201
            :.|..|:|||..||||||..|...||.||.|||.|:||||...||:...|..||::|..:|..:|
Mosquito   133 IREDTVETLLATACLLQLSTIVGACCNFLARQLHPSNCLGFSLFAEQQGCTALLKLATAYTCQHF 197

  Fly   202 QEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLL 266
            |:|.:::||.:|...||.:::.||:|||.:|::||:|:|:|::|:...|::|:.::|..::||||
Mosquito   198 QQVWKNQEFFMLDAAQLANLLRSDDLNVPNEQEVFHALMAWIQYDAEGRKRHIPELLALIKLPLL 262

  Fly   267 SPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWC 331
            .|.|:|..|  :.|......|:.||.||..:.|:|..|.|:...||||||.| .|.:| ||||..
Mosquito   263 QPSFIVDHV--EALCGGANECQQLVMEAFKWHLIPGRRSLISTSRTRPRKST-MGRLL-AVGGMD 323

  Fly   332 SGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQW 396
            ......|:|.:||:.:.|.::..|..||...|||||:|.|..|||.||...||:::.:|..|..|
Mosquito   324 GHKGAISIESYDPRLDKWTLLKNMPTRRLQFGVAVLDDKLIIVGGRDGLKTLNTVDSFDLNTMCW 388

  Fly   397 SCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAV 461
            |..|.|..:.|..:|||.|:|.||||||.||...||.|||:||....||.||||:..|....|||
Mosquito   389 STLVPPMGTPRHGLGVAFLEGPLYAVGGHDGWSYLNTVERWDPSARTWSYVAPMSAMRSTAGVAV 453

  Fly   462 LGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDC---- 522
            |||.||.|||.||.....|||.|||..|||...:||:.||..:|..|.|.::||:||. ||
Mosquito   454 LGGRLYVIGGRDGSVCHRTVECYDPHTNKWTLRAPMNQRRGCVGVGVLNGFLYALGGH-DCPPSN 517

  Fly   523 ---MELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQ 584
               ....:.|||:|.|:||:.|.:::..|..:|::|:...|.|:||:||..|||.:|.||.|||:
Mosquito   518 PAVCRTDTVERYDPTTDTWTLIASLSVGRDAIGVSVLGDWLVALGGYDGIQYLKIVEQYDAETNE 582

  Fly   585 WRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS 623
            |.....:||.|  .|..|:..|         |||..|.|
Mosquito   583 WTPIAPVNYSR--AGACVVAIP---------NSFSNPAS 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	62/128 (48%)
		PHA03098	69..587	CDD:222983	240/526 (46%)
		KELCH repeat	359..403	CDD:276965	20/43 (47%)
		KELCH repeat	407..451	CDD:276965	26/43 (60%)
		KELCH repeat	454..497	CDD:276965	23/42 (55%)
		KELCH repeat	501..545	CDD:276965	18/50 (36%)
		KELCH repeat	548..593	CDD:276965	19/44 (43%)
LOC1281663	XP_061497908.1	None