Protein Alignment dbo and klhl17

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_004916201.1
• Gene: klhl17 / 100491332
• XenbaseID: XB-GENE-977875
• Length: 627
• Species: Xenopus tropicalis
• Alignment Length: 560
• Identity: 281/560 - (50%)
• Similarity: 372/560 - (66%)
• Gaps: 7/560 - (1%)

  Fly    47 LSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQT 111
            :||.|::|.......:|.:|:...|||:||:||.::|..|:|:|::||.||.||||.|:.|||||
 Frog    52 ISHNSKRHYHDAFVCMNRMRQRGLLCDIVLHVGTKEIKGHKVVLASCSPYFHAMFTNEMSESRQT 116

  Fly   112 EVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLG 176
            .||:.|||..|:|.|:.:.|||.|:|.|.|||||||||.||||..::|.||:||..||||:||||
 Frog   117 HVTLHDIDPQALEQLVQYAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSNCLG 181

  Fly   177 IRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMS 241
            ||.|||||||.:||:.|.|:...:|.||.::|||:|||:.|::|:|.||.|||.|||:|:.||::
 Frog   182 IRGFADTHSCSDLLKSAHKYVLQHFVEVSKTEEFMLLPLKQVLDLISSDSLNVPSEEEVYRAVLN 246

  Fly   242 WLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPL 306
            |:|::|..||||:.::::.|||||||..||:.:|.::||||....|:||:.||..|.|:|::|.:
 Frog   247 WVKHDVDGRRQHVPRLMKCVRLPLLSRDFLMSSVDTELLVRHHSECKDLLIEALKYHLMPEQRGV 311

  Fly   307 MQGPRTRPRKPTRRGEVLFAVGGWCSGDAIA---SVERFDPQTNDWKMVAPMSKRRCGVGVAVLN 368
            :...|||||:......|||||||   |...|   ..|.:|.:|:.|.||..||.||..||||.:.
 Frog   312 LSNSRTRPRRCEGASTVLFAVGG---GSLFAIHGDCEAYDTRTDRWHMVTSMSTRRARVGVAAIG 373

  Fly   369 DLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNH 433
            :.||||||:||.|.|.::|.|||.||.|..:|:..|. |:.:|||||.|.|||.||.||..|||.
 Frog   374 NKLYAVGGYDGTSDLATVESYDPVTNTWQPEVSMGTR-RSCLGVAVLHGLLYAAGGYDGASCLNS 437

  Fly   434 VERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMS 498
            .|||||....|:.:|.|:|||..|.||.|.|.|||:||.|....|.|||:|:|:.|.|..::.|.
 Frog   438 AERYDPLTGTWTSIAAMSTRRRYVRVATLDGNLYAVGGYDSSSHLATVEKYEPQINTWTPIANML 502

  Fly   499 TRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAV 563
            :||...|.||....:|..||.|....|:|.|||||..|||..:..|..|||...|..::|.||||
 Frog   503 SRRSSAGVAVLEGMLYVAGGNDGTSCLNSVERYNPKANTWESVAPMNIRRSTHDLVAMDGWLYAV 567

  Fly   564 GGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVM 603
            ||.|||:.|.:||.|:|.||:|....||..||...||.|:
 Frog   568 GGNDGSSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	68/126 (54%)
		PHA03098	69..587	CDD:222983	268/520 (52%)
		KELCH repeat	359..403	CDD:276965	23/43 (53%)
		KELCH repeat	407..451	CDD:276965	24/43 (56%)
		KELCH repeat	454..497	CDD:276965	20/42 (48%)
		KELCH repeat	501..545	CDD:276965	18/43 (42%)
		KELCH repeat	548..593	CDD:276965	23/44 (52%)
klhl17	XP_004916201.1	BTB_POZ_KLHL17_actinfilin	38..176	CDD:349555	65/123 (53%)
		PHA03098	77..543	CDD:222983	243/469 (52%)
		KELCH repeat	321..360	CDD:276965	15/41 (37%)
		KELCH repeat	364..407	CDD:276965	23/42 (55%)
		KELCH repeat	411..454	CDD:276965	24/42 (57%)
		KELCH repeat	458..502	CDD:276965	20/43 (47%)
		KELCH repeat	505..549	CDD:276965	18/43 (42%)
		KELCH repeat	552..597	CDD:276965	23/44 (52%)
		Kelch	564..608	CDD:128874	24/44 (55%)