Protein Alignment dbo and kbtbd3

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_002934972.1
• Gene: kbtbd3 / 100490420
• XenbaseID: XB-GENE-6044137
• Length: 607
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 148/635 - (23%)
• Similarity: 247/635 - (38%)
• Gaps: 138/635 - (21%)

  Fly    13 PRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLN 77
            |||          :.|.|...|...|.:     ::|..||.|.:..|:.|...|..:...|..:.
 Frog     4 PRD----------SFGRGVCNGFPYVQK-----KISIVSECHGQQILSILQNFRDQKAFFDFNII 53

  Fly    78 VGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNV 142
            |..:.:..||.:|:|.|.:|.|||...::|.....|||.::..||:...:|:.||....:.:.||
 Frog    54 VKDQLMPCHRCVLAASSDFFRAMFEVNMKERDGGSVTISNLSSNAVAAFLDYAYTGKAEITDENV 118

  Fly   143 QTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMES 207
            ..|...:..||:..:...|.:||.:.:|..|||.:.:.::::....|...|.:|:..:|..:.:|
 Frog   119 DMLFQMSSFLQVPLLSKACSDFLIKIIDTNNCLQLLSISESYGSTRLFDHALEFSLQHFSLLTQS 183

  Fly   208 EEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLV 272
            .:||.|.:|.|...:..|.|||..||....||::|.|:::.:|.:...::|:.:||..||...|.
 Frog   184 TDFLELNIGVLEKCLEDDLLNVPEEESALVAVIAWTKHSLDKRERFFPRLLRTIRLHQLSQSTLQ 248

  Fly   273 GT-VGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAI 336
            .. :..|.|::|.: |...::.|                       .:|.|   |.||......:
 Frog   249 NVLISEDQLLKSTD-CLSTINSA-----------------------IKRVE---AAGGLFPDARL 286

  Fly   337 ASVER------------------FDPQTNDWKMVAPMSKRRC-GVGVAVLNDLLYAVGGHDGQS- 381
            ::.|:                  ::.:|:.|..:..:..... |..::...:.::..||..|..
 Frog   287 STTEKYIFVHKTAEDGGTQCTFCYNLKTDKWLELPHIQLTDLPGSSLSSYGEKIFITGGCKGHCC 351

  Fly   382 ---YLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENK 443
               .|:..|.|...|:|..|                                      |.|..|.
 Frog   352 RGVRLHIAEPYHDATDQTWC--------------------------------------YCPASNN 378

  Fly   444 WSKVAPM-TTRRLGVAVAVLGGFLYAIGGSDGQC----PLNTVERYDPRHNKWVAVSPMSTRRKH 503
            .|.|..| ..|.:..:|..|.. |:.|||.....    .|..||.|:|...:|.:|||:.....:
 Frog   379 SSLVPAMKKPRTMHTSVMALNQ-LFVIGGKTKGAHYIKSLLDVESYNPLAKEWKSVSPLPRGIYY 442

  Fly   504 LGCAVFNNYIYAVGGRDDCMELSSA--------ERYNPLTNTWSPIVAMTSR---RSGVGLAVVN 557
            ...:...|.||.:|..   :|::.|        .:||..||.|..:||...:   .:.:....||
 Frog   443 PEASACKNVIYVLGSE---VEITDAFNPSLDCFFKYNAETNQWCELVAEFGQFFHATLIKAVPVN 504

  Fly   558 GQLYAVGGFDGSAYLKTIEVYD--PETNQWRLCG---CMNYRRLGGGVGV 602
            ..||...       |.|.:||.  |||..|:..|   |..:.  .|.||:
 Frog   505 NTLYICD-------LSTYKVYSFCPETCVWKGEGSFECAGFN--AGAVGI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	37/126 (29%)
		PHA03098	69..587	CDD:222983	129/559 (23%)
		KELCH repeat	359..403	CDD:276965	10/48 (21%)
		KELCH repeat	407..451	CDD:276965	6/44 (14%)
		KELCH repeat	454..497	CDD:276965	14/46 (30%)
		KELCH repeat	501..545	CDD:276965	13/51 (25%)
		KELCH repeat	548..593	CDD:276965	14/49 (29%)
kbtbd3	XP_002934972.1	BTB_POZ_KBTBD3_BKLHD3	24..153	CDD:349580	39/128 (30%)
		PHA03098	62..582	CDD:222983	132/562 (23%)
		KELCH repeat	330..385	CDD:276965	15/92 (16%)
		KELCH repeat	389..437	CDD:276965	16/48 (33%)
		KELCH repeat	440..485	CDD:276965	11/47 (23%)
		KELCH repeat	537..582	CDD:276965	3/11 (27%)