Protein Alignment dbo and klhl10

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_012810304.1
• Gene: klhl10 / 100486163
• XenbaseID: XB-GENE-6047527
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 195/571 - (34%)
• Similarity: 283/571 - (49%)
• Gaps: 33/571 - (5%)

  Fly    20 GTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIF 84
            |.|..:..|.|...|..|.                       |..||:...||||.|:.||....
 Frog     6 GAGVGAGVGAGGCAGDCAT-----------------------LERLRQEGRLCDVELSAGGATFS 47

  Fly    85 AHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAA 149
            ||::||..|||||..:|||...:..::...|..:....:.|::||.||..:.|...|.:.|..||
 Frog    48 AHKIILCGCSSYFRQLFTGSWSDPMRSRYWIPGLSPEMLRLILDFAYTGAVGVTADNAEELFVAA 112

  Fly   150 CLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEV-MESEEFLLL 213
            ....::.:...|..|:..||.|.||||:..|:..:.|.||.:.|..|...:||:| .||.||...
 Frog   113 DQFSVMGVARACVAFMGSQLCPQNCLGMWRFSAYYPCPELRQRAHSFLLRHFQQVGAESPEFRTA 177

  Fly   214 PVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSD 278
            ...:|.:||.||:|||:.||.:|..::.|:|.....||..::.:|..|||.|::..:|:.||...
 Frog   178 APQELAEIIGSDQLNVQQEEALFQLIVQWIKMEPETRRDAISNLLPKVRLALMNTDYLLNTVQDH 242

  Fly   279 LLVRSDEACRDLVDEAKNYLL-LPQERPL---MQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASV 339
            ..|...|.|:.||..|..... |....|.   ...|.||||.|.   .:|||:|||......:::
 Frog   243 EYVAHSEPCQSLVTHALRLRYGLDMNGPSAFDFHNPLTRPRLPY---NILFAIGGWSGRSPTSAI 304

  Fly   340 ERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTT 404
            |.:|.:.:.|..:...|.|... |...|.:.:|.:||.|...|.|::.|:.....:|. :|:|..
 Frog   305 EVYDERADRWAELEGHSPRAYH-GAVFLGNFIYVLGGFDSADYFNTVRRFSLAQRRWE-EVSPMH 367

  Fly   405 SCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAI 469
            :.|..:.||||.|::||:||.||...||..|||.|..|:||.::.|..:|...:..||.|.:|..
 Frog   368 TRRCYLSVAVLHGYIYAMGGFDGYVRLNTAERYQPHTNQWSLISTMHEQRSDASATVLHGKVYIC 432

  Fly   470 GGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPL 534
            ||.:|...|.|.|.|.|..|:|..::||.:||..:|...|...|:||||.|....|:|||.|.|.
 Frog   433 GGFNGNECLPTAEVYSPDTNQWSLIAPMGSRRSGVGVVTFLEQIFAVGGFDGTERLNSAECYAPN 497

  Fly   535 TNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQW 585
            |||||....|.:.||..|:.|:..:|:.:|||:|:......|..|.:.|:|
 Frog   498 TNTWSQAPPMFNTRSNFGIEVLAKRLFVLGGFNGATTTCNAEYLDGDANEW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	40/126 (32%)
		PHA03098	69..587	CDD:222983	186/522 (36%)
		KELCH repeat	359..403	CDD:276965	11/43 (26%)
		KELCH repeat	407..451	CDD:276965	21/43 (49%)
		KELCH repeat	454..497	CDD:276965	15/42 (36%)
		KELCH repeat	501..545	CDD:276965	20/43 (47%)
		KELCH repeat	548..593	CDD:276965	13/38 (34%)
klhl10	XP_012810304.1	PHA03098	32..566	CDD:222983	186/522 (36%)
		KELCH repeat	323..366	CDD:276965	12/44 (27%)
		KELCH repeat	370..413	CDD:276965	21/42 (50%)
		KELCH repeat	417..461	CDD:276965	16/43 (37%)
		KELCH repeat	464..507	CDD:276965	20/42 (48%)
		KELCH repeat	511..554	CDD:276965	13/38 (34%)