DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dbo and si:ch73-29c22.1

DIOPT Version :9

Sequence 1:NP_524989.2 Gene:dbo / 53556 FlyBaseID:FBgn0040230 Length:623 Species:Drosophila melanogaster
Sequence 2:XP_021324659.1 Gene:si:ch73-29c22.1 / 100332572 ZFINID:ZDB-GENE-091204-309 Length:325 Species:Danio rerio


Alignment Length:298 Identity:130/298 - (43%)
Similarity:177/298 - (59%) Gaps:4/298 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   312 TRPRKPTRRG---EVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYA 373
            |:..|...:|   ::::.||||...|....||:|..|.|:||..|||...|...||..|:..:|.
Zfish    27 TKKNKAASKGKLSDMIYVVGGWSKDDPSCPVEQFCSQYNEWKFTAPMLHPRSDTGVCALDGDIYT 91

  Fly   374 VGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYD 438
            |||.|..:.|:|:|||.|::|.|:.||...:|.|:.|.|..:||.|..:||.||:.|:|.|||||
Zfish    92 VGGSDDVTCLSSVERYHPESNTWTVDVPSLSSPRSRVCVLEMDGCLITLGGFDGMTCINTVERYD 156

  Fly   439 PKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKH 503
            |.:|.|||:.||...|...:.|||.|.:|.:||:||...|::|||:||....|.....|||.|:.
Zfish   157 PLKNSWSKLTPMLRNRAAASAAVLNGQIYVVGGTDGDMALDSVERFDPFEGCWSLCPTMSTPREA 221

  Fly   504 LGCAVFNNYIYAVGGRDDC-MELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFD 567
            .|||||...:|..||||:. :.||:.|||:|....|||:.||.::|..|.|.|.|..|.|:||.|
Zfish   222 SGCAVFLGCLYVAGGRDELGLSLSNVERYDPDNFRWSPVRAMNNKRFQVSLVVFNDFLLAIGGSD 286

  Fly   568 GSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRA 605
            |.:..||:|.||.|||.||..|.|..:..||...:::|
Zfish   287 GVSDHKTMEAYDYETNSWRHFGSMKSKHPGGHAALVKA 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dboNP_524989.2 BTB_POZ_KLHL20_KLEIP 49..176 CDD:349558
PHA03098 69..587 CDD:222983 124/278 (45%)
KELCH repeat 359..403 CDD:276965 19/43 (44%)
KELCH repeat 407..451 CDD:276965 23/43 (53%)
KELCH repeat 454..497 CDD:276965 17/42 (40%)
KELCH repeat 501..545 CDD:276965 21/44 (48%)
KELCH repeat 548..593 CDD:276965 23/44 (52%)
si:ch73-29c22.1XP_021324659.1 Kelch 42..87 CDD:128874 19/44 (43%)
BTB <75..308 CDD:333434 107/232 (46%)
KELCH repeat 77..121 CDD:276965 19/43 (44%)
KELCH repeat 125..169 CDD:276965 23/43 (53%)
KELCH repeat 172..217 CDD:276965 18/44 (41%)
KELCH repeat 219..264 CDD:276965 21/44 (48%)
KELCH repeat 267..312 CDD:276965 23/44 (52%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D731760at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.920

Return to query results.
Submit another query.