DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbo and klhl20

DIOPT Version :9

Sequence 1:	NP_524989.2	Gene:	dbo / 53556	FlyBaseID:	FBgn0040230	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001135481.1	Gene:	klhl20 / 100216018	XenbaseID:	XB-GENE-960635	Length:	234	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	134/169 - (79%)
Similarity:	147/169 - (86%)	Gaps:	0/169 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELE 106
            |.|||:.:.|:|||:.||..:|:||:|||||||||.||.:||:||||||||||.||.|||||||.
Frog    38 PQPARMPYVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELA 102

  Fly   107 ESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDP 171
            |||||||.||||||.||||||||.||:.|.|||.||||||||||||||.|||:.|||||||||||
Frog   103 ESRQTEVVIRDIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDP 167

  Fly   172 TNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEF 210
            :||||||||||||||||||||||||||||||||.:|..|
Frog   168 SNCLGIRAFADTHSCRELLRIADKFTQHNFQEVRDSVLF 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	98/126 (78%)
		PHA03098	69..587	CDD:222983	120/142 (85%)
		KELCH repeat	359..403	CDD:276965
		KELCH repeat	407..451	CDD:276965
		KELCH repeat	454..497	CDD:276965
		KELCH repeat	501..545	CDD:276965
		KELCH repeat	548..593	CDD:276965
klhl20	NP_001135481.1	BTB	59..162	CDD:279045	83/102 (81%)
		BTB	69..165	CDD:197585	78/95 (82%)
		BACK_Kelch	165..>203	CDD:269808	35/37 (95%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	183	1.000	Domainoid score	I3381
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	960	1.000	Inparanoid score	I331
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	1	1.000	-	-		FOG0000036
OrthoInspector	1	1.000	-	-		oto103900
Panther	1	1.100	-	-	LDO	PTHR24412
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160