Protein Alignment dbo and si:rp71-68n21.9

DIOPT Version :10

• Sequence 1: NP_524989.2
• Gene: dbo / 53556
• FlyBaseID: FBgn0040230
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_021334567.1
• Gene: si:rp71-68n21.9 / 100151173
• ZFINID: ZDB-GENE-081105-100
• Length: 686
• Species: Danio rerio
• Alignment Length: 578
• Identity: 172/578 - (29%)
• Similarity: 272/578 - (47%)
• Gaps: 38/578 - (6%)

  Fly    41 PPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVG-GRKIF-AHRVILSACSSYFCAMFTG 103
            ||.|......|.:|....|..|:..|....||||.|..| ..:.| .||||:::.|.||.|||||
Zfish    73 PPKPQIQVFNSTEHGADILKGLDHFRGDETLCDVTLVPGDSSETFPVHRVIMASASDYFKAMFTG 137

  Fly   104 ELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQ 168
            .:.|....|:.:..:....::.:|.|.||:.:.:....:|..|.||..||::.:.:.|.:.|..:
Zfish   138 GMREQELKEIKLHGVSTVGLKNIIVFIYTSQLSLSLGTLQDTLEAASFLQVLPVLNFCNQLLSSE 202

  Fly   169 LDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEE 233
            :...||:.:...|......::.:....|...||..:|:|...|.|....:...:.|:.|...||.
Zfish   203 ITIENCVEVERIAKDLLLEDVQKHIHTFVCENFSMLMQSGRLLQLSEASMTFALSSNSLRGLSEM 267

  Fly   234 QVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSD---------------LLVRS 283
            :::....:||.:...|||.....:::|:|.||:||..|:.....|               ..:||
Zfish   268 ELYRIARAWLSHKPNERRSAAYSLMRHIRFPLMSPAELLQISQEDQTEEGAASKRKEEGEAFMRS 332

  Fly   284 DEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTND 348
            |.||.:|:.||.||.:||..:|.:|..||:.|.....   |..:||......:.|.|......:|
Zfish   333 DTACVNLLLEASNYQMLPFLQPALQTERTKIRSDCTH---LVVLGGVMRQQLVVSKELKLYNKDD 394

  Fly   349 ---WKMVAPMSKRRCGVGVAVLNDLLYAVGGHD-----GQSYLNSIERYDPQTNQWSCDVAPTTS 405
               |:.:.||...|...|||:|...||.|||..     |::.::|..||||:.::| ..||....
Zfish   395 GGSWRALQPMEVPRYQHGVALLGGFLYIVGGQSTYDTKGKTAVDSAYRYDPRFDRW-LQVASLNE 458

  Fly   406 CRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIG 470
            .||...::.|.|.||||||::....::.||.|:..:|:|:.||||:....|.|..|.||.:|..|
Zfish   459 KRTFFHLSALKGKLYAVGGRNATGEIDSVECYNLNKNEWTLVAPMSEPHYGHAGTVHGGLMYVSG 523

  Fly   471 GSDGQCPLNTVERYDPRHNKWV-AVSPMSTRRKHLGCAVFNNYIYAVGGR-----DDCMELSSAE 529
            |.........:..|:|..:.|. ....|..|..|..|.| ...:|.:||.     :|..::.|.|
Zfish   524 GITRDAFQKELLCYNPDRDVWSRRADMMELRGLHCMCTV-GERLYVMGGNHFRGTNDYDDVLSCE 587

  Fly   530 RYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGF--DGSAYLKTIEVYDPETNQW 585
            .|:|..:.|:.:..|...:|.||:||...::|.|||:  :....:..::.||||.::|
Zfish   588 FYSPDADQWTMVAPMPRGQSDVGVAVFEERIYVVGGYSWNSRCMVDIVQCYDPEKDEW 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dbo	NP_524989.2	BTB_POZ_KLHL20_KLEIP	49..176	CDD:349558	40/128 (31%)
		PHA03098	69..587	CDD:222983	164/550 (30%)
		KELCH repeat	359..403	CDD:276965	19/48 (40%)
		KELCH repeat	407..451	CDD:276965	18/43 (42%)
		KELCH repeat	454..497	CDD:276965	11/43 (26%)
		KELCH repeat	501..545	CDD:276965	12/48 (25%)
		KELCH repeat	548..593	CDD:276965	14/40 (35%)
si:rp71-68n21.9	XP_021334567.1	BTB_POZ	81..208	CDD:453885	38/126 (30%)
		BACK	203..298	CDD:475122	21/94 (22%)
		NanM	396..662	CDD:442289	81/252 (32%)
		KELCH repeat	408..456	CDD:276965	19/48 (40%)
		KELCH repeat	460..504	CDD:276965	18/43 (42%)
		KELCH repeat	507..552	CDD:276965	11/44 (25%)
		KELCH repeat	554..603	CDD:276965	13/49 (27%)
		KELCH repeat	606..646	CDD:276965	14/40 (35%)