DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment krz and saga

DIOPT Version :9

Sequence 1:	NP_001247400.1	Gene:	krz / 53554	FlyBaseID:	FBgn0040206	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_956853.1	Gene:	saga / 792319	ZFINID:	ZDB-GENE-040426-1538	Length:	392	Species:	Danio rerio

Alignment Length:	421	Identity:	185/421 - (43%)
Similarity:	265/421 - (62%)	Gaps:	55/421 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGR-EDLDVL 112
            ||||.|.:..:.||:|||||||.|..|||:|||:.||||.::.:|.:..:...||||| :|.:||
Zfish     7 VFKKISKDKSVGVYMGKRDFVDRVDSVDPVDGVILIDPEQLRGKKAYVTLSCVFRYGRDDDAEVL 71

  Fly   113 GLTFRKDLYLAHEQIYPPMQLDRP---MTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPAPG 174
            |::|||::|::..|:||.:| |:.   :|::||:|::|||.||:||:||.|...|.||.|||||.
Zfish    72 GISFRKEIYISTRQVYPALQ-DKEQCILTKVQEKLLRKLGDNAYPFFFEFPDNLPCSVGLQPAPK 135

  Fly   175 DVGKSCGVDYELKAFVGENVEDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNKIHL 239
            ||||.|.|::|:|||..|:.:.|..||:||.|.||||.|||.|:|..||:|.:::|:|....:||
Zfish   136 DVGKHCAVEFEVKAFCAESQDAKVRKRSSVGLMIRKVQYAPEKLGPAPSVETTRDFLMSDKPLHL 200

  Fly   240 EATLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDGCQV 304
            ||:|:|:.|:|||.|:|.|.:.|.||:.|:.|.:.|.|.|::.|:....|..|||..:|  |..|
Zfish   201 EASLEKQTYYHGEPINVRVKINNQSNKNVRNIILSVEQNANVVLYCNDNYMKVVATEDS--GHSV 263

  Fly   305 APGFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVKVKL 369
            ..|..|.||:.|.||||||:::.|:||||:|||||||||||::|....|:|.|||||.|:|.|||
Zfish   264 DSGAKLEKVYTLLPLLANNRERRGIALDGKLKHEDTNLASSSIIKEGVQKEVLGIMVSYRVVVKL 328

  Fly   370 LISSPLLNGDLVAELPFTLMHPKPEEEEHPLLGERSPRASLAGGGLPLVSMSDGETESATGGQDV 434
            ::...:.:.::..||||.||||||:                        ::.:.|.|
Zfish   329 IVGGMMGSSEVGVELPFQLMHPKPD------------------------AVKESEAE-------- 361

  Fly   435 PTTTNLIQLDDDEAQDDDIIFEDFARLRLKG 465
                            ::::||:|.|..|||
Zfish   362 ----------------EEMVFEEFKRTYLKG 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
krz	NP_001247400.1	Arrestin_N	59..214	CDD:419887	82/158 (52%)
krz	NP_001247400.1	Arrestin_C	233..393	CDD:214976	77/159 (48%)
saga	NP_956853.1	Arrestin_N	17..175	CDD:304627	82/158 (52%)
saga	NP_956853.1	Arrestin_C	194..352	CDD:214976	77/159 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595699
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	1	1.000	-	-		FOG0000854
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.820