DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment krz and Sag

DIOPT Version :9

Sequence 1:	NP_001247400.1	Gene:	krz / 53554	FlyBaseID:	FBgn0040206	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_037155.2	Gene:	Sag / 25539	RGDID:	3619	Length:	403	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	197/429 - (45%)
Similarity:	265/429 - (61%)	Gaps:	57/429 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGREDLDVLG 113
            :|||.|.:..:|:||||||::|||:.|:|:||||.:|||.||.:||:..:..|||||:||:||:|
  Rat    13 IFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVIG 77

  Fly   114 LTFRKDLYLAHEQIYPPMQLDRPMTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPAPGDVGK 178
            ||||:|||.:..|:|||:......|:||..|:||||.|.:||....|.|.|.||.|||||.||||
  Rat    78 LTFRRDLYFSRVQVYPPVGAMSAPTQLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGK 142

  Fly   179 SCGVDYELKAF---VGENVEDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNKIHLE 240
            |||||:|:|||   :.:..|||..|::||||.||||.:||.::|.||..|.|.:|.|....:||.
  Rat   143 SCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKVQHAPPEMGPQPCAEASWQFFMSDKPLHLS 207

  Fly   241 ATLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDGCQVA 305
            .:|.||:|.|||.|.|.|.|.||:.:.||||||.|.|.|::.|:|:..|...||..|:::  :|.
  Rat   208 VSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQE--KVQ 270

  Fly   306 PGFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVKVKLL 370
            |..||:|...|.||||||:::.|:||||::|||||||||||:|.....|..:||:|.|.:||||.
  Rat   271 PNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLT 335

  Fly   371 IS---SPLLNGDLVAELPFTLMHPKPEEEEHPLLGERSPRASLAGGGLPLVSMSDGETESATGGQ 432
            :|   ..|.:.::..|:||.||||:||                           |...||
  Rat   336 VSGFLGELTSSEVATEVPFRLMHPQPE---------------------------DPAKES----- 368

  Fly   433 DVPTTTNLIQLDDDEAQDDDIIFEDFARLRLK--GAETE 469
                           .||::::||:|||..||  |..||
  Rat   369 ---------------VQDENLVFEEFARQNLKDTGENTE 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
krz	NP_001247400.1	Arrestin_N	59..214	CDD:419887	90/157 (57%)
krz	NP_001247400.1	Arrestin_C	233..393	CDD:214976	77/162 (48%)
Sag	NP_037155.2	Arrestin_N	23..181	CDD:419887	90/157 (57%)
		Arrestin_C	200..361	CDD:214976	77/162 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..403		6/12 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	1	1.000	-	-		FOG0000854
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X758
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960